In acute attacks of gout, the pain relief time after taking colchicine varies from person to person. Some patients may feel pain relief within a few hours, but others may stop taking colchicine because they cannot tolerate the adverse effects of the drug. Colchicine is one of the drugs commonly used in the treatment of acute attacks of gout. In general, the pain and swelling of joints can be reduced within a few hours after taking colchicine. However, because colchicine has a high incidence of gastrointestinal adverse reactions, many patients have difficulty tolerating it and stop taking it. For such patients, non-steroidal anti-inflammatory painkillers can be used to control joint inflammation and reduce the symptoms of joint swelling and pain. In conclusion, no matter what kind of medication is used for gout patients, they should also strictly control their diet, abstain from alcohol, and maintain sufficient water intake.