The needle stabbed by syphilis should promptly wash the affected area with alcohol or soapy water, try to squeeze out the local blood from the needle stabbed place for timely treatment, more than ninety-five percent of syphilis patients are transmitted through sexual intercourse, a few infections may be due to blood transfusion, kissing or medical personnel inadvertently infected. After being stuck by a needle is not 100% will be infected, mainly depends on the strength of the body’s immunity. If the body’s immunity is strong, specific antibodies will appear in the sixth week after infection with the pathogen, to kill or dissolve the pathogen of syphilis, with the production of antibodies the body’s immunity is gradually strengthened, early syphilis can have the tendency to heal itself without treatment. If the body’s immunity is weak and spreads throughout the body, it is usually difficult to completely eliminate, resulting in the insidious development of syphilis or the development of advanced syphilis. Syphilis can be divided into one to three stages, of which the second stage syphilis is the most contagious, manifesting itself as a widespread syphilis rash on the skin and mucous membranes, while the third stage syphilis, also known as late syphilis, is not contagious, but the lesions usually involve the cardiovascular central nervous system to produce more serious consequences.