The bone marrow is responsible for the production of red blood cells and other immune cells. The cells contained in the bone marrow vary widely, but they all have to proliferate under the body’s control, and if something goes wrong in the middle of the process, it can be a disaster for the body, as in the case of myelodysplastic syndrome. Is myelodysplastic syndrome serious? It is a disease of abnormal proliferation of bone marrow hematopoietic stem cells, which usually occurs in the elderly. Under normal conditions, the bone marrow undergoes a series of complex evolutions to finally become blood cells and its other immune substances. Once the changes occur, prompting a massive proliferation of abnormal cells, its inevitable that the normal red blood cell production will be affected, leading to abnormalities in the surrounding blood cells and other test indicators. Whether the disease is serious or not depends on the situation. The disease does not metastasize throughout the body as other malignant tumors do, but the possibility of transformation into leukemia cannot be ruled out. It is very difficult to treat because of the drastic decrease in peripheral blood cells caused by this disease. This condition is also considered a serious disease. The diagnosis of myelodysplastic syndrome is not difficult and there is a clinical basis for the diagnosis of this disease. There are two prerequisites and more than one definitive condition that must be met. First, the necessary conditions Excluding other causes, continuous blood tests, found that red blood cells, white blood cells and platelets are below normal values. Second, the conditions for confirming the diagnosis: 1) abnormal bone marrow hematopoietic cells greater than or equal to 10%; 2) chromosomes associated with abnormal bone marrow hyperplasia; 3) a primitive cell percentage of 5% to 19% during the bone marrow smear; 4) ring-shaped iron-derived granulocytes accounting for more than or equal to 15% of nucleated red blood cells. These conditions to confirm the diagnosis, is to the professional physician to see, as ordinary people, we do not require to see, and this is necessary to do some tests as well as operations, to go to get the specimen, but also need the appropriate instruments, so, want to confirm the diagnosis of this disease, it is best to go to a professional hospital, do not listen to rumors to judge the condition on their own. The good thing is that this disease is not hereditary, although modern times have identified chromosomal abnormalities in about more than half of the patients. But there is no evidence to prove whether the abnormality is congenital or an acquired change. Therefore, patients suffering from this disease do not have to worry about passing it on to the next generation, and it is relatively more important to learn more about the disease. In life, if we find ourselves or people around us with pale eyelids and conjunctivae and pale lips, we need to be aware of whether we are anemic. This is because the most typical symptom of myelodysplastic syndrome is anemia.