In recent years, with the continuous development of new clinical drugs, medically induced liver injury has become a very important problem, involving almost 1000 drugs. Drug-induced liver disease accounts for about 10% of patients with clinical hepatitis, and the proportion can exceed 40% in patients over 50 years of age. In the 21st century, there are more than 30,000 kinds of drugs and health care products for human application, plus food additives and environmental pollutants, humans are being exposed to the threat of more than 60,000 kinds of chemicals. In other words: taking medicine can also produce hepatitis. Guo Changqing, Department of Gastroenterology, First Affiliated Hospital of Zhengzhou University When it comes to hepatitis, people naturally think of “hepatitis A”, “hepatitis B”, “hepatitis C”, “large and The hepatitis A, hepatitis B, hepatitis C, and major and minor triplets come to mind. In fact, in the hepatitis family, there are also alcoholic hepatitis, autoimmune hepatitis B, drug-related hepatitis and several other major categories. Among them, the harm is widespread, but people do not pay attention to the number of people suffering from drug hepatitis, unauthorized use of drugs beware of incurring drug hepatitis. When drugs enter the body, the main metabolism and detoxification site is the liver. If a drug has toxic side effects, the liver is the first to be damaged. In addition to the role of the drug itself, there is also a great relationship between individual differences and the situation of liver enzymes in the individual’s body. Drug-related hepatitis can be classified as acute, subacute, or chronic. In severe cases, fulminant liver failure can occur, with sudden massive necrosis of liver cells, and the patient may die within one to two weeks. Drug hepatitis can be a direct drug toxicity or an allergic reaction i.e. liver damage mediated by immune mechanisms. The initial symptoms may include fever, jaundice, rash or itching, peripheral blood eosinophilia, and elevated serum aminotransferases and alkaline phosphatase as the hallmark of laboratory tests for liver function. Chinese herbal medicines can also cause drug-related hepatitis. Many people think that Chinese herbal medicines are safe and have few toxic side effects and rarely cause liver damage. However, in recent years, it has been found that the number of adverse reactions caused by herbal medicines and their preparations has been increasing year by year. The reason for this, in addition to the residues of pesticides in cultivated herbs and species confusion, the toxic side effects of the herbs themselves cannot be ignored. According to the literature, the Chinese medicine “Jin Bu Xie pain relief tablets” has the effect of tranquilizing and relieving pain, as a traditional drug has been used in China for more than a thousand years, but some doctors found that: some individual patients in the average of twenty weeks after taking the regular dose of Jin Bu Xie tablets led to acute hepatitis, including patients with abdominal pain and jaundice, transaminases and serum alkaline phosphatase The liver biopsy confirmed that it was drug-induced hepatitis, and the patient returned to normal after stopping the drug, and there may be alkaloids in the drug tablets that cause liver cell damage. It can be seen that not all herbal medicines are very safe, and it is important to take herbal preparations in accordance with medical advice, avoid taking more than the prescribed amount and for a long time, not to take the drugs externally internally, and to take a cautious attitude towards folk single prescriptions to prevent poisoning. Therefore, it is important to cultivate the concept of scientific medical treatment and not to use drugs without authorization, so as not to incur the danger of drug-related hepatitis.