In 1994, the Austrian Urological Society proposed the term “partial androgen deficiency syndrome in middle-aged and elderly men” at the European Male Science Symposium. “In 2002, the International Society for the Study of Older Men renamed this syndrome “delayed hypogonadism (LOH)”, which objectively reflects the decrease of testosterone levels in middle-aged and older men with age, and was recognized by the International Society for the Study of Men and the European Society of Urology. The main cause of LOH is the partial lack of androgens and the decrease in the level of biologically active androgens in the body. The main clinical manifestations of LOH are: 1. neurological and vasodilatory symptoms manifested as hot flashes, excessive sweating, palpitations and nervousness. 2. emotional and cognitive dysfunction. Emotional and cognitive dysfunction: anxiety, poor self-perception, lack of motivation, decreased brain power, recent memory loss, depression, lack of self-confidence and unexplained fear, etc. 3.Physical and physical symptoms include insomnia or drowsiness, loss of appetite, constipation, skin atrophy, bone and joint pain, etc. 4, hypermasculinity symptoms manifested as physical fitness and energy decline, muscle volume and muscle strength decline, body hair loss and abdominal obesity, breast development, etc. 5.Symptoms of hypogonadism: decreased sexual desire, reduced or absent morning erection, reduced sexual activity, decreased orgasm, weak ejaculation, low semen volume and erectile dysfunction, etc. If you are over 40 years old and have the above symptoms of decreased sexual function and energy, you should be alert to the occurrence of LOH, and we recommend you to go to the hospital as soon as possible.