The World Health Organization defines male infertility as the failure to conceive for 1 year due to male factor in the case of normal sexual intercourse between a man and a woman who want to have children without using contraception. Male infertility is defined by time, not by semen indicators (such as sperm concentration, sperm viability, etc.). It is a very critical issue to distinguish between with and without disease, which directly determines the problem of standardized treatment and overtreatment: 1. Men and women who have not taken contraception for less than 1 year have the possibility of pregnancy and can be observed as long as there are active sperm in the semen, unless the patient is absolutely sterile (e.g., azoospermia, etc.). Once absolute sterility is diagnosed, the treatment process of male infertility can be entered. The probability of pregnancy for couples of childbearing age is 75% for six months, 85% for one year, and 90% for some information. 2, male infertility is also closely related to the age of the female partner, age and human fertility have a close relationship. Male or female are at the peak of fertility around the age of 25. Compared to younger men at 25, men over 40 are 50% less likely to impregnate their female partners within 1 year, and men over 45 take longer (about 6 times longer) to impregnate their female partners than 25-year-old men. The effect of age on female fertility is even greater. When women reach 35 years old, their fertility decreases to 50% of that of 25 years old; when they reach 38 years old, it decreases to only 25%; when they are over 40 years old, it is less than 5%. Therefore, female spouses who are over 35 years old and have not taken contraceptive measures for more than six months without pregnancy can enter the stage of infertility treatment. 3.If there are family factors, or if one of the infertile couples is suspected of having infertility factors, the examination of infertility need not be postponed until one year later. 4. Semen indicators cannot be simply used to assess male fertility. In 2010 to 2011, a sperm bank donor sperm college students, graduate students of the semen routine standard rate of only 22.5% to 35.9% (of course the selection criteria of donor volunteers is significantly higher than the standard of normal people), we can not say that those volunteers whose semen indicators do not meet the standard of low fertility or sterility, the same reason, can not say that infertility patients with problems with semen indicators, it means that he can not In the same way, we cannot say that a patient with infertility has a problem with semen indicators and that he cannot be fertile. In order to clarify the issue of male fertility with and without disease, we need to further understand what primary male infertility and secondary male infertility are. Primary male infertility is if a man has never impregnated a woman; secondary male infertility is if he has ever impregnated a woman and is facing infertility problems; and a woman, whether she is his current lover or another woman, as described above. Male doctor tips: laboratory tests and medication are only part of the professional doctor’s diagnosis and treatment of the disease, see the doctor is never a list of prescriptions for drugs, for male fertility abnormalities, must be combined with the medical history for analysis. The definition of male infertility is defined as the absence of pregnancy for one year due to male factors, which is defined by time, not by semen laboratory indicators (such as sperm concentration, vitality, malformation rate, etc.), when both men and women are not using contraception and have a normal sex life. The definition of primary male infertility and secondary male infertility mainly depends on whether the male patient has made the female partner have a history of pregnancy or not.