Glutamyl transpeptidase is widely found in liver cells, intrahepatic cholangiocytes, and renal tubular epithelial cells, and is a transfer enzyme of an amino group involved in the synthesis of glutathione. This index can be used clinically to assess whether the function of the liver is normal or not, and its normal value ranges from 3-50 U/L. If the test result is 64 U/L, it means that it is higher than the normal value, and it is an abnormal condition. The causes of elevated glutamyl transpeptidase include physiologic and pathologic. Physiologic is mainly caused by severe fatigue and frequent late nights; pathologic is mostly seen in cirrhosis of the liver, acute hepatitis, cholangitis, kidney diseases, etc. Generally speaking, the value of glutamyl transpeptidase alone cannot determine the specific cause of the disease, and it is necessary to analyze the condition in combination with other auxiliary examinations and clinical symptoms. For patients with mildly high glutamyl transpeptidase and no other abnormalities, they can first pay attention to improving their lifestyle, such as quitting smoking and drinking, eating a reasonable diet, avoiding late nights and overwork, and needing regular checkups. If the value of glutamyl transpeptidase still cannot be reduced to normal by improving lifestyle, it is necessary to go to the hospital as soon as possible to clarify whether there are other pathologic factors, and then give the corresponding treatment according to the cause of the disease.