A cold does not affect thyroid nodules, which is a generic term for swollen lesions in the thyroid gland that are associated with the patient’s eating habits and mental stress. Colds are usually caused by upper respiratory infections and are not directly related to thyroid nodules. Subacute thyroiditis, which is characterized by pain and discomfort in the neck, can be diagnosed by blood tests and ultrasound of the thyroid gland. After the diagnosis of subacute thyroiditis, hormone therapy is usually required and can be cured over time.