Stage I syphilis is curable. First, it is important to understand what stage I syphilis is. The characteristic manifestation of stage I syphilis is a hard chancre, which is found on the penis, glans, prepuce, urethra and coronal groove; in women, on the labia, clitoris, cervix, anus and perineum; it can also appear on the tongue, lips and breasts. The characteristics of hard chancre appear 7-60 days after infection with the syphilis spirochete. In most people, the hard chancre manifests as a single, painless, non-itchy, round or oval, small ulcer with very clear borders, the ulcer is high on the skin surface, the surface is clean and dry, some patients with secondary infection may have increased secretion, the ulcer is relatively hard cartilaginous feeling when touched by hand, lasting 4-6 weeks, most people may not Note that the slow self-healing, this time period will be accompanied by proximal lymph node enlargement. Stage I syphilis is treatable, as long as early diagnosis, early treatment, standardized application of drugs can be cured. Nowadays, the commonly used clinical medication is penicillin preparation, such as penicillin G, benzathine penicillin (long-acting cillin) in two buttocks intramuscularly once a week, the course of treatment is 3-4 times, or intramuscularly with procaine penicillin G for 10-15 consecutive days. For patients who are allergic to penicillin, erythromycin, doxycycline, tetracycline and doxycycline can be used, which are the drugs of choice for the treatment of syphilis. Phase I syphilis can still be cured with timely treatment.