Hepatic coma, also known as hepatic encephalopathy, is a serious complication of cirrhosis, based on metabolic disorders of the central nervous system syndrome, after the onset of consciousness and coma, once the deep coma is difficult to wake up again, often causing life-threatening to patients, what are the first symptoms of hepatic coma? What are the precursors to the onset of hepatic coma? Hepatic encephalopathy is one of the common and serious complications of heavy hepatitis, cirrhosis and hepatocellular carcinoma in the late stage, if not detected and treated in time, it can seriously endanger patients’ lives, so patients with cirrhosis and hepatocellular carcinoma and their families need to know what are the precursors of hepatic encephalopathy in time, so that abnormalities can be detected in time and targeted treatment or care can be given in time to prevent the disease. What are the aura of hepatic coma? The early stage of hepatic coma is mainly characterized by mild personality changes, behavioral disorders, and disorientation, comprehension and other relative loss of performance, common symptoms are mainly agitation or indifference, depression or euphoria, hyperactivity or slow action, unkempt clothing or anywhere defecation behavior disorders, to take patients to the hospital for examination and treatment in a timely manner, do not delay the disease. Liver coma mainly occurs in patients with cirrhosis and hepatocellular carcinoma in the middle and late stages. Common causes include high protein diet, massive diuresis or ascites discharge, upper gastrointestinal hemorrhage, azotemia, sedative and sleeping drugs, infection and hypoxia, surgery, anesthesia, constipation or uremia, etc. It is mostly seen after various kinds of cirrhosis and portal shunt, so in order to effectively reduce the incidence of liver coma, patients with cirrhosis and those who have undergone portal shunt Therefore, in order to effectively reduce the incidence of hepatic coma, patients with cirrhosis and those who have undergone portal shunts need to take preventive measures in a timely manner and actively avoid the occurrence of the above-mentioned adverse triggering factors; acute hepatic coma often occurs in patients with acute hepatic failure and can often enter coma quickly due to acute massive hepatocyte necrosis, and patients still need to take timely protective measures.