The cold weather in winter brings inconvenience to people’s lives and also leads to the recurrence of many diseases, and winter is also a high season for liver disease. The effects of cold on the human body are many. Chronic liver disease patients how to safely winter, from what aspects should be noted, for many chronic liver disease patients are concerned. 1, correct understanding, mood relaxation. Maintain a good state of mind, emotional optimism, is conducive to the recovery of liver disease. Chronic liver disease patients due to long illness, long treatment, especially in winter, the cold weather, go out activities are restricted, some appear irritable mood, easy to lose temper, some appear depressed mood, the treatment of liver disease lost confidence. The above state of mind is extremely detrimental to the recovery of liver disease. Therefore, liver disease patients should be in a relaxed mood, should be optimistic, open-minded spirit, to establish a strong confidence to overcome the disease. Because when people are in a depressed state, the physiological functions of the body are also at a low tide, immune function, resistance to disease are in a low state. Only when the mood is full and the spirit is high, the level of various hormones in the body can secrete normally, and the immune function and the ability to resist disease can play its leading role. 2, pay attention to keep warm, prevent colds. Due to the change of climate, colds are common and frequent in winter. For patients with liver disease, especially those suffering from chronic liver disease, there is a risk of serious complications caused by colds. Patients with liver disease should not take colds lightly and must pay attention to increasing and decreasing clothes with the warm and cold weather and pay attention to keeping warm. Pay special attention to winter foggy weather, air pollution is heavy, as little as possible outdoor activities; as little as possible to crowded places such as theaters, shopping malls, etc.. Patients with chronic liver disease are already sick and weak, and their immune function is low, so viruses, bacteria, fungi and other pathogenic factors often take advantage of the situation, so patients with liver disease often catch colds and pharyngitis, skin boils, bronchitis, pneumonia, pleurisy, urinary tract infections and other diseases, so that the disease that has been at rest or tends to heal is active and worsening again. Therefore, patients should pay extra attention to diet, personal hygiene and other aspects. The patient should take part in physical exercise and increase or decrease clothes with the change of temperature to prevent the recurrence of liver disease. It has been shown that most of the winter recurrences of chronic hepatitis are caused by colds. In addition, the anti-allergic ingredients (such as paracetamol, etc.) and antipyretic and analgesic ingredients (acetaminophen, aspirin) in the cold treatment drugs are metabolized in the liver, thus increasing the burden on the liver and making it worse for patients with liver disease. 3, work and rest, pay attention to rest. Live a regular life and ensure enough rest and sleep. When resting in bed, the blood flow to the liver increases by 30%, and lying down can increase the blood flow to the liver, reduce the functional damage to the liver and help liver cell repair and regeneration. So rest plays a very important role in the prognosis of hepatitis patients. It is important to avoid overexertion, because overexertion itself is one of the triggering factors of chronic liver disease. The more active a person is, the less blood flow to his or her liver, and the less nutrients the liver receives. Overexertion can also reduce the body’s immune function and easily invite other bacterial and viral infections. However, prolonged bed rest is also not conducive to the normal metabolism of the body and can cause obesity, which can induce the formation of fatty liver, and may also increase the mental burden of the patient, which is also not conducive to the recovery of liver disease. Therefore, we should combine work and rest, and patients with stable liver disease should be appropriately active, especially in sunny, less foggy weather appropriate outdoor activities, will be beneficial to the mood, but should avoid excessive exercise, in order not to feel fatigue as degree. 4.Fine match, balanced diet. If liver disease patients choose to eat food monotonous or improperly handled for a long time, or because of partial eating, picky eating, avoid eating and other bad eating habits and make the intake of certain nutrients insufficient, too much to choose to eat tonic drugs or indiscriminate use of drugs and cause food and digestion and absorption and poor utilization, etc., can cause nutritional deficiency disease, can aggravate the liver disease; protein supply is insufficient or malabsorption, can make Inadequate protein supply or malabsorption can slow liver cell repair, which can easily lead to liver sclerosis and ascites. Patients with liver disease who overeat or consume some high-sugar, high-protein diet for a long time and consume too much more than their body needs will develop fatty liver while causing obesity, and may also add hypertension, coronary heart disease and other diseases, bringing adverse effects to the recovery of liver disease. Therefore, we cannot overemphasize the “three highs and one low” diet of high sugar, high protein, high fiber and low fat. The diet for patients with chronic liver disease should be based on the principle of protecting the liver from further damage and reducing the burden on the liver, all liver-damaging drugs and alcoholic beverages must be avoided, and animal fats containing more saturated fatty acids should be restricted. Patients with chronic liver disease can make use of the nourishing function of protein to assist their recovery. Mandarin fish, eel and yellow fish can be consumed alternately, while carp and black fish are more suitable for those with liver and kidney yin deficiency. Chicken and lamb are low-fat, high-protein foods with a sweet and warm nature, which are beneficial to those with low liver function and weak spleen and stomach. Beef, which is sweet and mild in nature, can also strengthen the spleen and stomach and replenish qi and blood. Rabbit meat is sweet and cool in nature, which can nourish the middle and benefit the qi and cool the blood and detoxify the toxin, which is especially suitable for external damp-heat cases. Especially in winter, you may choose the above meat to eat properly, but less hot pot and half-cooked food. Note also that plant and animal proteins should be reasonably matched, and the ingested proteins are broken down into amino acids after digestion in order to be absorbed, and then manufactured in the liver into proteins that are the most important muscle and blood components for humans. When animal and plant proteins are reasonably matched and provided in a balanced manner every day, they can make up for their respective deficiencies, significantly increasing the utilization of protein and ensuring the full absorption and utilization of essential amino acids. Excess protein is the basis for fat gaining and fat storage in the form of fat. A day to eat too much meat, eggs, chicken and fish, the actual absorption increased, while the real use of only the daily requirement. Excess protein instead increases the burden on the liver, to convert it into fat storage, resulting in artificial fat and even fatty liver. Biologists have found that when you eat protein foods and vegetables together, the stomach’s digestive juices are much more than when you eat a single food, so you should never ignore the complementary effects of melons, vegetables, fruits and cereals on protein. Honey, fresh vegetables and fruits can enhance the immunity of the body, which is especially beneficial for patients with deficiency evidence of liver disease. Also pay attention to avoid eating all kinds of spicy food, avoid smoking and alcohol. Smoke contains a variety of toxic substances that can damage liver function and inhibit liver cell regeneration and repair. Alcohol is extremely harmful to the liver and has a direct damaging effect on liver cells. The ethanol and nitrosamines in alcohol can cause liver steatosis, alcoholic hepatitis, liver fibrosis and liver cancer. Therefore, patients with liver disease should strictly quit smoking and drinking. 5, reasonable treatment, timely review. Be sure to use drugs under the guidance of a specialist. Patients with chronic liver disease should not use drugs casually, especially not too many drugs, because many drugs have to be metabolized by the liver, which will increase the burden on the liver, as little as possible, in order to achieve the purpose of protecting the liver, what we call liver-protective drug therapy, is a kind of palliative care, chronic liver disease exists because of the role of hepatitis virus damage to liver cells, now, chronic liver disease is mainly because of chronic The most fundamental treatment is antiviral therapy. The currently recognized effective antiviral treatments for chronic hepatitis B are interferon and nucleoside analogs; for chronic hepatitis C are interferon or plus virazole (ribavirin). For asymptomatic patients with chronic hepatitis, medication is generally not required. Some patients always think that if they have a disease, they must take medication and feel safe with medication, but in fact, most patients with hepatitis B and C do not need medication. Inappropriate medication is not only unsafe, but often also causes drug-related hepatitis or other related adverse drug reactions. 6, hepatitis patients receiving drug therapy should strictly comply with medical advice, adhere to the medication on time, not three days to fish and two days to sunbathe. If you do not take your medication on time will affect the efficacy, but also increase the adverse effects of drugs, antiviral drugs also tend to cause drug resistance phenomenon. The right amount of vitamin supplements can help hepatitis treatment. Clinically, vitamin C has been found to help improve liver function and promote metabolism. Vitamin E can protect polyvalent unsaturated fatty acids, reduce tissue oxygen consumption, and also protect damaged liver cells. B vitamins are more closely related to the liver, and are indispensable and important substances involved in the metabolism of sugar, fat and protein in the body, so vitamin B complex should also be supplemented in appropriate amounts to facilitate liver function recovery. The above drugs are only used as auxiliary drugs for the treatment of liver disease, and 1~2 kinds can be selected appropriately. In short, it is appropriate to use less medication. Patients with chronic liver disease should review liver function, hepatitis B or C serum virological index, abdominal ultrasound and methemoglobin in a timely manner. Self-perception should be the main focus, if there is weakness, loss of appetite, yellow urine and other conditions need to promptly seek medical advice. There are also a lot of chronic hepatitis symptoms are not obvious, but the disease is still progressing, until the development of liver stiffness ascites or even liver cancer to seek medical attention, so it is too late. Therefore, you should have regular checkups and timely review of liver function and ultrasound to provide a basis for doctors to guide treatment. Generally speaking, for patients with chronic liver disease, liver function can be checked every 3 months, viral serology index every 3-6 months, abdominal ultrasound and methemoglobin every 6 months to 1 year.