Alkaline phosphatase is a widely distributed enzyme in the human body, which is mainly distributed in the liver, bones, kidneys and intestines, and is an enzyme excreted from the liver to the outside of the bile. Low alkaline phosphatase may be caused by physiological reasons, and it is recommended to review the indicator after three months to determine if the phosphatase is low in healthy people. Low alkaline phosphatase can also be caused by pathological reasons. Generally speaking, alkaline phosphatase activity can be in the normal range or low in viral infections; low alkaline phosphatase can occur in severe chronic nephritis and thyroid insufficiency; low alkaline phosphatase can also occur in hereditary hypophosphataseemia. When women have low alkaline phosphatase, they should first check the cause of low alkaline phosphatase, which is usually caused by anemia and chronic nephritis. If it is caused by anemia, it can be improved by diet modification; if it is caused by other diseases, the patient must go to the hospital for a detailed examination to clarify the cause and treat the symptoms. In clinical cases of low alkaline phosphatase, most patients can be corrected by diet, as in the case of anemia. For more serious diseases, treatment is needed according to the cause, such as dialysis for chronic nephritis, and intravenous or enteral nutrition support for certain malignant tumor patients.