1, infection: due to leukemia caused by normal leukocyte reduction, especially neutrophil reduction, while chemotherapy and other factors also lead to the lack of granulocytes, making patients vulnerable to serious infections or sepsis. Some patients treated with corticosteroids are more susceptible to viral infections, such as varicella zoster virus and herpes simplex virus, due to low cellular immune function. Pneumocystis carinii infection is also common, and upper respiratory tract infection and pneumonia are its common types. 2, intestinal failure: due to the treatment of leukemia in chemotherapy drugs, radiotherapy means affect the gastrointestinal function, and lead to fear of gastric failure, the patient’s nutritional supplementation has become a prominent problem, the current use of subclavian vein cannula to the superior vena cava for high nutrition infusion only solve part of the problem, nutritional deficiency can occur pneumonia, enteritis and other complications. 3, hyperuricemia: normal people excrete 300-500mg of uric acid in the urine daily due to the metabolic decomposition of nucleic acid. leukemia patients can increase the amount of uric acid excretion tens of times due to the decomposition of nucleic acid in a large number of leukemia cells. When patients receive chemotherapy, radiotherapy and other treatments, hyperuricemia occurs, and the application of corticosteroids can increase hyperuricemia. High concentrations of uric acid quickly supersaturate and precipitate, causing extensive damage to the kidneys and uric acid stones, which can lead to oliguria and anuria. Therefore, patients with leukemia must be supplemented with more adequate fluids to ensure a certain amount of urine. 4, bleeding: Patients with leukemia are prone to respiratory, gastrointestinal and urinary bleeding, especially intracranial bleeding, due to malignant proliferation of leukemic cells and significantly reduced platelets, so active hemostatic measures should be taken according to the cause, including transfusion of concentrated platelets. Disseminated intravascular coagulation: Disseminated vascular is a group of serious bleeding syndromes. 5. Pulmonary disorders: Due to the decrease in normal mature neutrophils and reduced immune function in leukemia patients, it often leads to lung infections. In addition, leukemia cells, infiltration can block small blood vessels in the lungs, bronchi and respiratory distress syndrome, chest X-ray can have hairy glass or corn network, can be experimental treatment of lung radiation. 6, electrolyte imbalance: white pressure disease treatment process is often due to excessive destruction of leukemia cells or excessive potassium excretion due to chemotherapy drug renal damage and other reasons. Also due to chemotherapy caused by poor appetite for food, digestive system dysfunction, incorporation of insufficient amount and resulting in hypokalemia. Or, increased phosphorus release due to leukemia cell destruction, resulting in low calcium, etc. Therefore, it is important to pay attention to electrolyte concentrations such as potassium, calcium and sodium during the treatment process.