Definition of osteoporosis: a systemic bone loss disease with chronic low back pain and even deformity and fracture as the main manifestation. It is a systemic bone disease that predisposes middle-aged and elderly people to suffer from. Osteoporosis is a systemic bone disease characterized by a decrease in bone mass and microstructural destruction of bone manifested by an increase in bone fragility, resulting in a greatly increased risk of fracture, which can easily occur even with minor trauma or without trauma. Osteoporosis is a chronic, multifactorial disease. There are usually no specific clinical manifestations until a fracture occurs. The disease is more common in women than men, and is commonly seen in postmenopausal women and the elderly. With the increase of the elderly population in China, the incidence of osteoporosis is on the rise and is a health concern in China and worldwide. Osteoporosis was introduced by Pornmer in 1885, but people’s understanding of osteoporosis has gradually deepened with the development of history and technological advances. In the early years, it was generally considered that a decrease in bone mass throughout the body was osteoporosis, while in the United States, fractures in the elderly were considered osteoporosis. It was not until the 3rd International Symposium on Osteoporosis held in Denmark in 1990 and the 4th International Symposium on Osteoporosis held in Hong Kong in 1993 that osteoporosis was given a clear definition and recognized worldwide: primary osteoporosis is a systemic bone disease characterized by a decrease in bone mass and degeneration of bone microstructure, resulting in an increase in bone fragility and susceptibility to fracture. International Osteoporosis Day is celebrated every year on October 20.