Hepatocellular carcinoma is not hereditary, but there is a certain tendency of family gathering 1. Mothers who suffer from hepatitis B virus infection and become long-term virus carriers may transmit the virus to their newborns during or after childbirth. Since the immune function of the newborn is not yet complete, it cannot effectively clear the virus and form continuous infection, resulting in chronic hepatitis, liver cirrhosis and finally liver cancer. 2, the family members of hepatitis patients are in close contact, such as one infected with hepatitis B virus, it is easy to unknowingly spill over to others. 3.The dietary habits and lifestyles of a family are basically the same, so the chances of exposure to cancer-causing factors are also basically equal. As to the cause of cancer in a family, the consensus view is that any cancer is the result of two mutations in the genes of cells. In patients with sporadic non-familial cancers, both changes occur after birth. In contrast, patients with familially predisposed cancers are already under attack by this cancer-causing factor before their mothers become pregnant. When they are born, the cells in their bodies already have a cancer-prone change, and after birth, they only need to suffer another attack from the cancer-causing factor to develop cancer, so their chances of developing cancer are higher than the average. This is the famous “two strikes theory”. Therefore, although liver cancer is theoretically not hereditary, it has a tendency to accumulate in families, so family members of the patient should pay attention to it. Members of a family with a history of liver cancer should be alert to this disease. To cut off the tendency of liver cancer gathering, we can start from changing bad dietary habits such as pickled food and salted vegetables, not eating moldy food, not drinking alcohol and eating more dietary fiber; advocate vaccination against hepatitis B virus, and for couples who are infected with hepatitis B virus, they should block the transmission of virus between mother and child under the guidance of doctors; in addition, maintaining an optimistic psychology is also an important part of liver cancer prevention.