The use of cimetidine is generally not an option for treatment of methylaminoaviromectin poisoning. Avermectin is a neurotoxic agent, methylamino avermectin poisoning is common in oral poisoning, its acute toxic side effects of the target organ is located in the nervous system, usually need to be treated with early emetic therapy, gastric lavage, if necessary, naloxone can also be used to release the central inhibitory effect of the poison. Ventilator-assisted respiration is necessary in case of coma and respiratory depression. Cimetidine is mainly used to inhibit the secretion of gastric acid, is a kind of H2 receptor antagonist. It is commonly used in the treatment of gastrointestinal ulcers and is generally not used in the treatment of metamizolamine poisoning. If a patient develops methylaminolevulinic acid poisoning, he or she needs to be taken to the hospital immediately, and delayed treatment may be life-threatening.