Diabetic nephropathy is one of the major complications of diabetes, with 30% of type I diabetes and 20-50% of type II diabetes being complicated by this disease. In China, 33.6% of hospitalized diabetes have diabetic nephropathy. And 25-40% of patients with renal failure are caused by diabetic nephropathy. Cardiovascular disease is also one of the major complications of diabetes. The incidence of coronary heart disease is 3-5 times higher than that of non-diabetes, and can be manifested in severe cases as angina pectoris, acute coronary syndrome, myocardial infarction, heart failure, arrhythmia and sudden death. The complications of diabetes are mainly caused by a series of enzyme and metabolite changes caused by hyperglycemia resulting in tissue cell and intracellular mitochondrial damage. These complications are exacerbated by hypertension and hyperlipidemia. Cardiac ultrasound was reported for 412 cases of diabetic nephropathy, which showed enlarged left atrium and left ventricle of the heart, left heart hypertrophy, and ventricular diastolic insufficiency. The severity was related to weight, age, degree of anemia, amount of urine protein, and degree of impaired renal function. The reason is that edema, hypoproteinemia, anemia, and hypertension of nephropathy will increase the burden on the heart. Therefore, diabetic nephropathy requires more attention to protect the heart. To avoid serious heart complications, we should pay attention to controlling diet and weight, controlling blood sugar, lowering hypertension and hyperlipidemia, correcting anemia, and treating urinary protein. Emphasis on a reasonable diet is one of the important measures to prevent and treat diabetic heart disease. By controlling calories, maintaining ideal body weight, appropriately increasing dietary fiber intake, ensuring the supply of essential inorganic salts and trace elements, and providing abundant vitamins, it is beneficial to prevent and treat diabetic heart disease. Daily cholesterol intake should be controlled below 300mg. Eat small and frequent meals and avoid overeating to prevent the occurrence of myocardial infarction. Salt intake should be limited to 2-5g per day to reduce the burden on the heart. Use less or no strong tea, coffee, chili, mustard, tobacco, alcohol and other foods that excite the nervous system.