Difficulty in throat more than two months after heart valve replacement may be due to upper respiratory tract infection, pharyngitis, tonsillitis caused by postoperative immune deficiency, which can be treated by general therapy, medication, and so on. 1. Upper respiratory tract infection: discomfort in the throat two months after heart valve replacement surgery is usually not related to surgery, and may be caused by upper respiratory tract infection. If it is a bacterial infection, you can use cephalosporin, amoxicillin and other drugs to treat it, and at the same time, drink more water and avoid eating stimulating food. 2. Acute pharyngitis: acute pharyngitis can also cause discomfort in the throat, in daily life, the patient should avoid excessive use of the voice, do not eat spicy and stimulating food, increase the intake of water to protect the pharyngeal mucosa, if there is an increase in white blood cells and other drugs such as roxithromycin capsule can be used for treatment. 3. Acute tonsillitis: Acute tonsillitis can cause symptoms such as enlarged tonsils and sore throat. It can be treated by gargling with compound chlorhexidine gargle, antibacterial treatment with penicillin, cephalosporin and other drugs if necessary, and nebulization treatment with budesonide suspension if the symptoms are serious. Heart valve replacement surgery more than two months of throat discomfort may also be other reasons, should be timely to the hospital for diagnosis and treatment. The above drugs need to be standardized under the guidance of the doctor, to avoid blind use of drugs, aggravate the condition.