Heart valve disease requires valve replacement to address anatomical damage. Artificial valves are categorized as: biologic valves and mechanical valves. Mechanical valves are generally suitable for patients of any age; their main component is pyrolytic carbon, i.e., a valve made of carbon that is processed at high temperature and high pressure, with properties similar to those of synthetic diamond, which is extremely hard. It is characterized by its durability, and when placed in the human body, contact with the blood can produce blood clots, requiring patients to take lifelong anticoagulants. Bioflaps are made from the pericardium of pigs and cows after a series of chemical treatments. Its characteristics are: good biocompatibility, do not need to take anticoagulants; but long-term work will be fatigue damage, especially in the age of 50 years old patients will be applied to accelerate the destruction. Therefore, the choice of valves for clinical use should be based on the patient’s specific situation. For example, age, co-morbidities, and convenience of anticoagulant application. The bioprosthetic valve may be considered in young female patients who wish to have children after surgery and who are ready for reoperation. The use of anticoagulants is an important factor. Anticoagulants are controlled after discharge from the hospital, but over- or under-dosing can occur due to many factors. It is usually necessary to check the prothrombin time monthly at a hospital above the county level and adjust the dosage according to the changes.