In the 1960s, cryotherapy was used for the treatment of superficial hemangiomas and achieved certain results. This method uses strong low temperature to condense the skin, hemangioma and the tissues surrounding the hemangioma, forming ice crystals in the cells and causing the cells to rupture, disintegrate and die, and then the hemangioma disappears through the repair process of the body. However, children are prone to complications such as cold urticaria, cold precipitation fibrinogenemia and cryoglobulinemia after this treatment, and the extremely low temperature of liquid nitrogen may lead to adverse reactions such as hyperplastic or atrophic scar, hyperpigmentation or hypopigmentation, cornual rash and tissue contracture. However, it has recently been reported that the application of milder cryosurgery (-32°C) can reduce scarring and pigmentation, etc., but the efficacy needs to be further confirmed.