Lack of corresponding emotional response to external stimuli, coldness to friends and relatives, loss of interest in things around, dull facial expressions, lack of inner experience, or rich inner thoughts that flow very little to the outside; lack of interest in people or things, no sense of responsibility, no care for people, no compassion, often showing an expression of indifference to things. Deep inside, most of these people are filled with loneliness and desolation, always with distrust and dissatisfaction with the outside world, suspicious of touching events, and even refusing to be touched. Pathological reaction 1, “physiological”, manifested as a lack of response to emotions, sluggishness, lack of interest in people or things, no sense of responsibility, do not care about people, do not like to deal with people. Even with their closest family members, they are unable to establish a real and deeper emotional attachment to them. This type of physically apathetic person is born with low skin temperature and slow heart rate. 2. The extreme sadistic type, with torturing and killing as the main behavior, has no sense of shame or morality for their actions, and shows a clear anti-social personality disorder. How to check that you are emotionally indifferent? Cranial CT examination. The patient loses emotional response to changes in the surrounding environment. In severe cases, they are indifferent to their physical health, live a lazy life, do not groom themselves, or even do not cut their hair or wash their faces. There is also little response to hunger and pain. They are also indifferent to national events, exciting news, difficulties at home, and family misfortunes.