The care of puerperal depression should start from the perinatal period, and the main care measures are as follows: 1. use various channels such as maternity school from the perinatal period to let pregnant women know about pregnancy and childbirth, and reduce the fear of pregnancy and childbirth; 2. give more care to pregnant women with family history of mental illness, and avoid all adverse stimuli; 3. In the process of childbirth, medical staff should give full care, love and patience, and let pregnant women understand that childbirth is a natural and normal physiological process. And now can also take labor analgesia, reduce the pain of pregnant women, reduce the fear of pregnant women on childbirth. For pregnant women with long labor and relatively large fetus, they should also give full encouragement and tell them the reasons why they can deliver normally; 4. Reduce unnecessary indications for cesarean section to avoid increasing the fear of pregnant women; 5. For pregnant women with previous history of bad pregnancy and delivery, they should tell her the reasons for bad pregnancy and delivery in detail and patiently, so that she can increase her self-confidence and believe that she can have a normal and healthy baby in the future.