Depending on the cause of the wrist pain, there are different ways to relieve it. If it is caused by long-term chronic exertion, reduce the movement of the painful joint and avoid weight bearing. If the pain is caused by an infection, cold compresses can be applied to relieve the redness and swelling. If the pain is severe, consider taking oral non-steroidal anti-inflammatory drugs as prescribed by your doctor to relieve the pain.