If large bumps appear on the face, which are hard to touch and painful, they are mostly considered to be boils caused by acne or bacterial infections, and need to be solved by a combination of skin management and medication. 1. Skin management: Keep your face clean, wash your face with milder cleaning products every day, and do not over-wash your face to avoid causing damage to the stratum corneum. Pay attention to avoid picking and squeezing with your hands to avoid spreading the infection. If the infection on the face spreads into the blood, it can easily cause intracranial infection. 2. Medication: Topical anti-inflammatory and anti-infective medication can be used, such as Nafloxacin cream, Adapalene gel, Fusidic acid cream or Mupirocin ointment. If it is caused by acne, it can also be combined with oral vitamin capsules. If it is caused by a boil, it needs to be combined with oral antibacterial agents. Azelaic acid can also be used, which has a therapeutic effect on both inflammation and acne, and can also reduce post-inflammatory hyperpigmentation. It should be noted that all the above medications should be used regularly and quantitatively under the guidance of a doctor. At the same time, daily attention should be paid to avoiding spicy, irritating and fried foods, and one should drink more water and maintain a light diet, etc. In addition, if the situation is difficult to control, you need to promptly go to the dermatology department for examination and treatment.