1, anticoagulants and their use Because the artificial valve and blood contact easily cause platelet coagulation, the formation of thrombus, anticoagulation is not enough to cause thromboembolism and other malignant consequences, anticoagulation in excess, it leads to bleeding, so a very important link after valve replacement is proper anticoagulation. Warfarin: once a day, keep the prothrombin time (PT) 18–36 seconds, or international normalized ratio (INR) 1.5–3.0, stop the drug of the day when trauma blood, gum bleeding or subcutaneous bleeding occurs, and check the PT in time. avoid the simultaneous application of blood-activating and blood-stasis drugs. After discharge, check PT at 1 week, 2 weeks, 1 month, 3 months, 6 months until adjusted to one stable dose of warfarin, which can be checked every 3 to 4 months. Start reducing the dose on the second day of each menstrual period, and start resuming the original dose after the menstrual bleeding period. Sauerkraut, carrots, cauliflower and spinach can affect the efficacy of warfarin and should be eaten sparingly. 2, heart function maintenance medication Digoxin: 0.5-1 tablet/dose once daily for 1 to 3 months or longer. Stop when pulse is <70 beats/min. Diuretics: Hydrochlorhexidine 25-50 mg/dose 1-3 times daily for 1 to 3 months or longer Antiseptic 20-40 mg/dose 1-3 times daily for 1 to 3 months or longer. It must be taken when coughing while lying down, coughing white foamy sputum, abdominal distension, swelling of both lower limbs occur. You can adjust the dosage and duration of medication by yourself, and prescribe Fosamax (tachyphylaxis tablets) in severe cases. Captopril: 12.5 - 25mg/time 2 times a day, for patients with large heart and high blood pressure, long-term use can improve heart function. Betalactam: 6.25 - 25 mg/dose 2 times daily, for patients with rapid atrial fibrillation (heart rate over 100 beats/min) and large heart and high blood pressure. 3.In case of cold and fever, cough and coughing up pus sputum, apply antibiotics intravenously in time. 4.After valve replacement, you usually need to rest for 3-6 months. During the rest period, you can take a walk and do light housework activities, and you should gradually increase the amount of activity to the extent that you do not feel strained. 5, review, after valve replacement, although the patient's symptoms have been significantly improved, but in order to maintain good heart function and keep the normal operation of the prosthetic valve, must adhere to regular follow-up, keep in touch with the doctor, to facilitate timely detection of problems and timely treatment.