Gliomas mainly present with symptoms of increased intracranial pressure such as headache, vomiting, and optic papillar edema, as well as symptoms of limited nerve damage. Gliomas grow aggressively, without envelope, with unclear demarcation and varying degrees of malignancy. It is prone to recurrence and dies in late stages from brain herniation. Expert advice: Once you find out that someone around you has this symptom, you should go to the hospital immediately for examination and diagnosis and treatment. Glioma examination items: 1. Cerebrospinal fluid examination: the pressure of lumbar puncture is mostly increased, some tumors located on the surface of the brain or intracerebral ventricle, the amount of cerebrospinal fluid protein can be increased, the number of white blood cells can also increase, some can be detected tumor cells, but the intracranial pressure is significantly increased, lumbar puncture may promote the risk of brain herniation, so generally only when necessary, if necessary, to identify with inflammation or hemorrhage, the pressure increased significantly. The operation should be cautious, do not put more cerebrospinal fluid, give mannitol drip after the operation, and pay attention to observation. 2.Ultrasonic examination: It can help to fix the side and observe whether there is hydrocephalus, and B-type ultrasonic scan can be performed through fontanel for infants, which can show tumor images and other pathological changes. 3.Electroencephalography: The EEG changes of glioma are on the one hand the changes of brain waves confined to the tumor site, and on the other hand the changes of frequency and amplitude which are widely distributed in general. In the more benign astrocytomas and oligodendroglial tumors, the main manifestation is limited delta waves, and some of them can be seen as epileptic waveforms such as spikes or sharp waves, while large glioblastoma multiforme can show extensive delta waves, sometimes only on the fixed side. Clinical diagnosis of glioma is based on: 1. Progressive intracranial pressure increase symptoms: headache, vomiting, vision loss, diplopia, seizures and psychiatric symptoms. 2. Focal symptoms resulting from pressure, infiltration and destruction of brain tissue: such as hemiparesis, aphasia, unstable walking and other symptoms. 3.Head CT, MRI, cerebral angiography: showing characteristic occupying metaplasia images can confirm the diagnosis. 4.The lesion is usually firstly manifested as a painful mass: in the advanced stage of the tumor, the symptoms (abnormal sensation, loss of sensation, and eventually loss of movement) caused by the loss of neurological function are gradually obvious. 5. Physical examination may reveal a deep mass: it is cemented to the main structures and pressure or palpation may cause involvement pain or abnormal sensation. The features of neurofibromatosis type 1 are obvious. In patients with neurofibromatosis, nodules or masses that were previously painless and stationary gradually grow and become symptomatic, and early diagnostic measures are taken to determine whether malignancy has occurred. Differential diagnosis of glioma: Diagnosis is made based on its age, sex, site of occurrence and clinical course, and its pathological type is estimated. In addition to the medical history and neurological examination, some ancillary tests are needed to help localize and characterize the diagnosis. Positron emission tomography can obtain images similar to CT and can observe the growth and metabolism of the tumor and identify benign malignant tumors.