Patients with thyroid nodules should not be treated with loose nodules cream. The nature of thyroid nodules should be clarified by applying specific methods of ultrasound exploration and cytological aspiration for pathology. If the nodules are considered benign, small or asymptomatic through ultrasound, clinical observation or appropriate application of eugenol can be used to control the growth and development of thyroid nodules. Pathological puncture and highly suspicious of malignant changes in thyroid nodules should be managed surgically as much as possible, including removal of thyroid nodules or radical thyroid cancer treatment to remove the surrounding lymph nodes. If there are no significant changes and the function is normal, it is best not to use medications. Thyroid nodules can be prevented by regulating the diet and avoiding spicy and irritating foods, as well as iodine-rich foods.