The efficacy and prognosis of depression treatment depends to some extent on the patient’s own understanding of depression and cooperation with the doctor. The following points are summarized in the hope that they will be helpful to depressed patients. (1) Depression is in most cases a self-limiting illness with a good prognosis in most cases. (2) Depression is never the result of any weakness of character, not a personality defect, but a disease, like hypertension and diabetes, with objective biological changes, so do not have any sense of shame. (3) The recovery of the disease is often not smooth, there will be fluctuations and recurrence, treatment must be persistent. (4) Antidepressants are not addictive, and for patients with a first episode, antidepressant treatment should last for at least one natural period of the episode (6-12 months). Adequate dosage and full course of treatment can minimize relapse. Take medication today in order to stop taking medication in the future as much as possible, therefore, do not just stop taking medication. (5) Grey mood is a manifestation of the disease, just like a cold and fever, which will go away with the wind as soon as the disease gets better. Always remind yourself not to be swayed by the gray mood, to try to maintain a positive attitude. (6) Regular exercise can relax your mood and help you recover from depression, but it cannot completely replace medication. (7) Taking a leave of absence may worsen the depressive condition. It is not recommended to take a leave of absence from school or long-term sick leave, but to try to integrate into society and actively restore social functions. (8) Try not to make major decisions during treatment, such as in marriage and work.