Diarrhea and anal pain can be divided into three main cases: first, anal inflammation, long-term diarrhea when the stool stimulates the anal local skin, resulting in anal congestion, edema, inflammatory changes, causing anal pain, can be treated with oral montelukast, bifidobacteria, anal pain can mostly disappear on its own after the diarrhea is cured. The second, anal fissure, most often in patients with long-term constipation, clinical manifestations in order to post-anal dripping blood, anal pain, can be accompanied by anterior sentinel hemorrhoids, once diagnosed with anal fissure, should actively perform surgical treatment. Third, hemorrhoids, when the acute attack of hemorrhoids formed thrombosed external hemorrhoids, can be accompanied by severe anal pain, diarrhea can cause anal pain than before, need to carry out surgical treatment. If you have diarrhea with anal pain, you should go to a regular medical institution to seek medical attention, identify the cause, and choose a reasonable treatment plan under the comprehensive assessment of a specialist, which can be cured.