In recent weeks, the weather has turned cold suddenly in the north and south of the Yangtze River, inside and outside the Great Wall, and the ground is prone to freezing in the morning and evening. Elderly people, for various reasons, have poor motor coordination and are more prone to fall, leading to fractures. And for the elderly, osteoporosis is one of the most common high-risk factors. Generalized pain, difficulty getting up, reduced height, hunchback and occult fractures are the most common manifestations of osteoporosis. Generally speaking, each person’s skeletal minerals reach their peak around the age of 30, which is medically known as “peak bone mass”. The higher a person’s peak bone mass, i.e., the more “bone mineral bank” reserves in the body, the later the onset of osteoporosis in old age, and the less severe it will be. Osteoporosis is a common systemic bone disease in middle-aged and elderly people. Its main characteristics are low bone mineral content, destruction of bone structure, reduced bone strength, and susceptibility to fracture. In addition to congenital gender, race, age, family history and acquired medications, diseases, nutrition and lifestyle, old age, female menopause and male hypogonadism are the causes of osteoporosis. In addition, diabetes, rheumatoid arthritis, ankylosing spondylitis and other diseases combined with osteoporosis also occur. When it comes to this, some people think that osteoporosis is a phenomenon unique to the elderly and has nothing to do with young people. In fact, it is not. If young people lack exercise, have poor diet structure and habits, have a thin body type and smoke and drink heavily, it is difficult to reach the ideal peak bone mass at a young age, resulting in osteoporosis in young people, especially young women. Therefore, the prevention and treatment of osteoporosis should be taken seriously from young people. Some people think, “I have osteoporosis anyway, basically there is no cure, so just live from day to day. In fact, from the perspective of treatment, no matter young or old, once osteoporosis is confirmed, timely standardized drug treatment, scientific adjustment of lifestyle and effective gradual exercise will definitely reduce pain and improve the quality of life. Here, some people will ask, “How can we be sure that we have osteoporosis? Some people say that the diagnosis can be determined by testing with a bone density measurement machine, but in fact, it is not, why? You say for example, when measuring lumbar spine bone density, due to degenerative changes in the lumbar spine vertebrae, marginal osteophytes will lead to high measurement values and affect the judgment; using the T value of BMD less than -2.5 to characterize osteoporosis also cannot be the gold standard, because there are differences in the parameters of different instruments, and parameter adjustment of the measured values is needed. Therefore, confirming the diagnosis of osteoporosis needs to be combined with the patient’s medical history and BMD test to make a comprehensive determination. In conclusion, osteoporosis is a silent killer that needs to be given high priority by the general public. Do not think that it is a minor disease of simple back and leg pain, and there is no need to make a fuss about it and treat it arbitrarily on your own. Once you have persistent low back, chest and back pain with light rest and heavy activity; or pain in the root of the thigh after light exercise; or persistent pain in the wrist and ankle caused by a slight sprain, you must go to a specialist hospital for timely examination, accurate judgment and scientific treatment. Otherwise, this silent killer will come unannounced and leave you bedridden, or even disabled and dead.