There are not only inter-individual differences in the age, speed, maturity and degree of pubertal development, but also obvious differences between races and genders. In China, it is generally stipulated that the second sex characteristics such as enlarged breasts appear before the age of 8 for girls and the first menstruation before the age of 10; for boys, the second sex characteristics such as enlarged testicles appear before the age of 10 and are accompanied by excessive physical development, which is called precocious puberty. Precocious puberty is found to be treated in a timely manner, mainly the following programs: 1, drug therapy: (1) GnRHa preparations: treprostinil and leuprolide acetate, which can competitively inhibit their own secretion of GnRH and reduce pituitary gonadotropin secretion, thereby inhibiting or delaying gonadal development. (2) Third-generation aromatase inhibitors: Letrozole, which has been found to be effective in peripheral precocious puberty, reducing the amount of vaginal bleeding, lowering estrogen levels, and reducing average ovarian volume. (3) Chinese herbal treatment: such as anti-premature granules, premature 3 granules, Chai Hu Dredging Liver San, and phlegm-diffusing formula are also applied. (2) Etiological treatment: For non-specific precocious puberty, the etiological treatment should be emphasized, such as surgical treatment of tumor in the saddle area of the head, or congenital adrenal cortical hyperplasia combined with precocious puberty should be treated with cortisol at the same time. The causes of precocious puberty in children are different, so you must go to a specialist to get a clear diagnosis before deciding on a treatment plan.