The pathological pattern of hepatocellular carcinoma can be divided into giant, nodular, diffuse and small carcinoma types: 1. The giant type is often a single carcinoma mass, or it can be a large mass formed by multiple nodules, sometimes there are small scattered carcinoma nodules in its vicinity; the diameter of the carcinoma mass is usually above 250px, with pseudo-envelope formation. 2.Nodular type is more common, which can be single or multiple nodules of different sizes scattered in the liver, with indistinct demarcation from surrounding tissues. The formation of multiple cancer nodules may be the result of cancer cells spreading through portal vein, or the occurrence of multi-centered cancer tissues. This type is mostly associated with cirrhosis and has a high degree of malignancy. 3.Diffuse type is rare, the nodules are usually small, similar in size, grayish-white in color, spreading all over the liver and accompanied by cirrhosis. Sometimes it is difficult to distinguish from cirrhotic nodules, and the disease develops rapidly and the prognosis is extremely poor. 4.Small carcinoma type is divided into small carcinoma type which is less than 3cm in diameter. The pathological characteristics of small carcinoma type include: intact envelope; less incidence of cancer embolus; less combined cirrhosis; better differentiation of cancer cells; more peri-cancer lymphocyte infiltration; good immune status. The prognosis is good, mostly single node. Histological pathology: 1. Hepatocellular type originates from hepatocellular epithelium and accounts for viii platinum of common clinical hepatocellular carcinoma. The cancer cells are mostly polygonal or round, arranged into nests or cords, with large nuclei and obvious nucleoli, and between the nests or cords, there are abundant blood sinuses and no interstitial components. 2.Cholangiocarcinoma originates from bile duct epithelial cells, which is rare clinically. The cancer cells are square or columnar in shape, arranged into glands, with more fibrous tissues and less blood sinuses. 3.Mixed type of the above two types exist at the same time or in a transitional form, not exactly like liver cells or bile duct cells, which is rare.