Many hepatitis B patients and hepatitis B carriers are eager to breastfeed their babies, but they have to give up for fear of infecting their babies with the hepatitis B virus. In fact, the amount of virus in breast milk is far less than that in blood, and the transmission of hepatitis B virus is mainly through blood and body fluids. With the assistance of hepatitis B immunoglobulin and hepatitis B vaccine combination vaccine, breastfeeding will not increase the chance of infection for babies. The principles of breastfeeding selection for this group are: simple hepatitis B carriers, newborns born with hepatitis B vaccine, can choose to breastfeed; small triple-positive pregnant women are tested for viral replication of HBV-DNA during pregnancy, if the viral load is very low or no viral replication, newborns born with hepatitis B vaccine can choose to breastfeed; HBV-DNA positive or large triple-positive mothers, suggesting that viral replication is in Mothers with positive HBV-DNA or major triple-positive, suggesting that the virus replication is active and breast milk is highly contagious, may inject one hepatitis B immunoglobulin in the 7th, 8th and 9th months of pregnancy to reduce the chance of intrauterine vertical infection; after the birth of the newborn, inject hepatitis B immunoglobulin and hepatitis B vaccine respectively within 1 month, at 1 month and at 6 months of age to implement combined immunization and breastfeeding. However, it should be noted that breastfeeding is not recommended for mothers with major triple-positive disease with abnormal liver function. However, hepatitis B and its carriers should pay attention to the following matters: wash your hands before breastfeeding and gently wipe your nipples with a warm clean towel before breastfeeding your child; the child’s and mother’s supplies should be separated, towels and basins for scrubbing and water cups for drinking should be used independently; infants who are in a position to do so should be tested regularly for antibodies to hepatitis B antigens; and direct transmission should be prevented. Skin and mucous membrane ulcers or ruptures are channels for hepatitis B virus transmission. Mothers with hepatitis B should pay special attention to using the correct breastfeeding posture, and should temporarily stop breastfeeding once a nipple is cracked or a baby has an oral ulcer to reduce the chance of the virus entering the baby’s bloodstream directly, and continue breastfeeding after the wound or mucous membrane has recovered. During the suspension of breastfeeding, the mother should also insist on expressing milk every day to prevent a decrease in milk volume or withdrawal when breastfeeding resumes.