Penile cancer is mainly diagnosed through ultrasound examination, visual examination and key pathological examination. Penile cancer mainly manifests as lumps in the penis and blood in urine. At the same time, ultrasound or CT examination can detect the occupying lesion of penis, and then puncture biopsy of the occupying lesion of penis can find cancer cells. Most of the pathological types of penile cancer belong to squamous carcinoma, and if squamous carcinoma cells are found in the puncture biopsy, penile cancer can be diagnosed. The main treatment for penile cancer is radical surgery and postoperative adjuvant radiotherapy and chemotherapy. Penile cancer is a malignant tumor with good prognosis and the treatment is mainly surgery.