Lead poisoning can be determined by history of lead exposure, clinical manifestations and auxiliary examinations. 1. History of lead exposure: for example, inhalation of lead dust or vapor in the working environment; or use of lead-containing eating utensils or taking excessive lead-containing drugs in daily life. 2. Clinical manifestations: Acute lead poisoning can mainly manifest as abdominal cramps, anemia and toxic hepatitis. In severe cases, toxic nephropathy and toxic encephalopathy may occur. In addition, there may be nausea, vomiting, metal taste in the mouth, dizziness, fatigue and other symptoms. 3. Auxiliary examination: the upper limit of normal value of blood lead is 400μg/L, and the increase suggests recent lead exposure, which is not necessarily related to the total amount of lead in the body. The upper limit of urinary lead is 70μg/L, which has the same significance as that of blood lead, and is easily contaminated by environmental factors and fluctuates greatly. Neuromuscular examination showed slowing of peripheral sensory and motor nerve conduction. Liver and spleen damage can be seen in some imaging tests of lead poisoning. If there is any discomfort, it is recommended to consult a doctor in time and follow the doctor’s instructions to carry out standardized treatment, such as lead expulsion, after a clear diagnosis.