Depression can be treated and cured. In the clinical treatment of depression subtypes, mild depression can be clinically cured through psychotherapy and self-adjustment. For example, through active exercise and creating structure in life so that the self is fully motivated to engage in activities that interest them. For patients with moderate and severe depression or above, pharmacological treatment is needed as the basis, such as applying selective pentoxifylline reuptake inhibitors, such as paroxetine, sertraline, fluoxetine, venlafaxine, escitalopram and other drugs as the first-line drugs for systematic and standardized treatment, to achieve adequate amount, full course and whole course of treatment. In addition to medication, self-adjustment and psychotherapy are also needed. In terms of the whole treatment process, psychotherapy is mainly to improve the cognitive function of patients, while self-adjustment is mainly to establish the structure of life as the main rehabilitation content.