The surgical treatment of primary liver cancer has developed rapidly in recent years, with surgery as the main method, supplemented by interventional therapy, local treatment of liver cancer such as radiofrequency, freezing, microwave, local lesion ethanol injection, and integrated treatment such as chemotherapy, biotherapy and immunotherapy. The progress of comprehensive treatment for liver cancer has opened up new horizons for the treatment of liver cancer, making the diagnosis and treatment of the disease more standardized and scientific, and improving the diagnosis rate, success rate of surgery and cure rate of primary liver cancer. Surgical treatment occupies the most important position, but the mode and focus of surgical treatment for liver cancer will change, and its role may also be given new vitality by the advancement of other therapies, especially local treatment and biological treatment. Combination therapy becomes the main modality of liver cancer treatment. With the progress of research on prevention of recurrence and metastasis, the efficacy of hepatocellular carcinoma surgical treatment will certainly be significantly improved. Relying on the “Chronic Liver Disease Treatment Center” of Dalian Sixth People’s Hospital, the Department of Hepatobiliary Surgery has treated a large number of primary liver cancer patients, of which 20% are treated by surgery, and combined with interventional treatment and other comprehensive means, the cure rate of liver cancer has been greatly improved and a standardized treatment model has been formed, which is at the upper level in China. We welcome patients with liver disease to come and see us.