Early diagnosis of tyrosinemia type I is the key to successful treatment, and low-phenylalanine and tyrosine diet therapy is used as early as possible in life to reduce the level of tyrosine concentration in blood and urine to improve clinical symptoms and stop the progression of the disease, but there is no good strategy to prevent the occurrence of hepatocellular carcinoma. Liver transplantation has also been reported. Tyrosinemia type II is treated with a low-phenylalanine and tyrosine diet as early as possible in the postnatal period to reduce tyrosine levels in the blood and urine, improve clinical symptoms and stop the progression of the disease, but there is no strategy to prevent the development of hepatocellular carcinoma. Early treatment of tyrosinemia type III can prevent the development of mental retardation. Early adoption of a low-phenylalanine and tyrosine diet can reduce the level of tyrosine in blood and urine, and rapidly improve clinical symptoms such as eye and skin and stop the progression of the disease. The main prevention of tyrosinemia is to restrict phenylalanine and tyrosine diet, correct hypoglycemia, hypokalemia, alkalosis and bleeding tendency. The only effective treatment is early liver transplantation. Also regular checkups are still necessary.