The current common worldwide standard for liver transplant timing is the MELD index. This index is a risk index calculated from indicators such as patient age, total bilirubin, serum creatinine and international standard ratio of prothrombin time. It reflects the risk of liver transplant patients during the waiting time for liver transplantation and an objective indicator of surgical risk. When the MELD index >12 points, it enters the waiting list; 18-25 points, the best time for surgery; 26-32 points, the recommended time for surgery as soon as possible; >32 points, the complication rate increases significantly; >40 points, the mortality rate increases significantly. Therefore, for those patients with cirrhosis who have low long-term survival, liver transplantation is recommended at lower levels of MELD, which can reduce the risk of surgery and save costs. Because for patients with end-stage cirrhosis, liver transplantation is the only hope for long-term survival for these patients.