Prevention and treatment of fatty liver disease

  In recent years, with the continuous improvement of people’s living standard, the change of diet structure, lifestyle and the increase of alcohol consumption, the incidence of fatty liver disease in China has been increasing year by year, and now it has become the second largest liver disease after viral hepatitis, and the age of the disease has a tendency of low age. Research data shows that fatty liver disease can progress to end-stage liver disease such as cirrhosis and hepatocellular carcinoma, and can also promote the occurrence of cardiovascular and cerebrovascular diseases, and other hazards.  Generally speaking, we often divide fatty liver disease into two categories according to the cause: non-alcoholic fatty liver disease and alcoholic fatty liver disease, and according to the degree of development of the disease, that is, the degree of liver damage is divided into: alcohol or non-alcohol-related simple fatty liver, hepatitis, liver cirrhosis and liver cancer, which means that if the fatty liver stage is not taken seriously and allowed to develop, the final condition is the same as chronic hepatitis B and C. If the fatty liver stage is not taken seriously and left to develop, the disease may eventually progress to advanced liver disease stages such as cirrhosis and liver cancer with poor prognosis. The risk factors associated with non-alcoholic fatty liver disease often include: 1) a high-fat, high-calorie diet; 2) a sedentary lifestyle; 3) metabolic disorders such as obesity, hypertension, dyslipidemia and type 2 diabetes mellitus, while the risk factors associated with alcoholic fatty liver disease are clearly the result of long-term heavy alcohol consumption.  Four aspects of a healthy lifestyle are promoted today: proper diet, moderate exercise, smoking cessation and alcohol restriction, and psychological balance. The first three of these 4 healthy lifestyles have a direct correlation with the prevention of alcohol or non-alcohol related fatty liver disease.  Why is there a direct correlation between diet, exercise, and alcohol consumption and fatty liver? The following is a specific discussion of the causes of fatty liver: it should be said that fatty liver is not an independent disease, it is a metabolic disease caused by a variety of factors or diseases that cause excessive accumulation of fat in the liver cells, and older individuals are often prone to develop with hypertension and diabetes. There is evidence that fatty liver occurs mainly due to the following six causes: 1, alcohol: long-term alcohol consumption (daily alcohol consumption converted to alcohol > 40g/d (alcohol conversion formula: g = alcohol consumption (ml) × alcohol content (%) × 0.8 (alcohol specific gravity), slightly lower for women, more than 5 years in a row) can lead to alcoholic liver disease, and the initial manifestation of alcoholic liver disease is alcoholic fatty liver. The cause is that alcohol and its metabolites can interfere with the metabolism of fatty acids by liver cells, thus causing fatty liver caused by fatty deposits in the liver. 2, excess nutrition: long-term consumption of high-fat, fried foods and sweets, so that the liver fat synthesis is excessive. 3, obesity. 4, diabetes: about half of type II diabetic patients with fatty liver, which is closely related to diabetes patients prone to disorders of lipid metabolism. 5. Hyperlipidemia. 6, malnutrition: due to malnutrition can lead to protein deficiency is an important cause of fatty liver, that is, excess nutrition belongs to too much raw materials, while malnutrition belongs to the processing of auxiliary materials are not enough, the same can not produce a qualified product, thus causing excessive accumulation of fat in the liver, resulting in fatty liver. In addition to the above six main causes, there are some rare causes that can also cause fatty liver: such as drug-related fatty liver (such as adrenocorticotropic hormones), pregnancy fatty liver, etc.  Here is what we can do to prevent the occurrence of fatty liver. First, treatment should be directed at the cause of the disease. For example, those who drink a lot of alcohol for a long time should stop drinking. Those who are over-nourished and obese should strictly control their diet and lose weight. Diabetic patients with fatty liver should control blood sugar. Patients with malnourished fatty liver should increase nutrition appropriately, and those with medicated fatty liver should reduce or discontinue relevant medications as much as possible.  Second, lifestyle intervention: pay attention to good lifestyle habits, which include both diet and exercise.  In terms of diet, it is important to control the diet, seven or eight minutes full is sufficient, and no additional meals before bedtime. It is recommended to consume foods with high protein, high fiber, low sugar and low fat, less sweets, fried foods, animal offal, etc. Long-term heavy drinkers should quit drinking.  In terms of exercise, emphasis on aerobic exercise, that is, the frequency of exercise to 3 days a week – 5 days is more appropriate, each exercise time to 15 minutes or more, preferably to reach more than 30-60 minutes, the size of the exercise to achieve faster breathing, exercise pulse of 170 minus the actual age, lasting thirty minutes, slightly sweating and then adhere to the exercise for a period of time is appropriate.  In addition, medication adjuvant therapy is also an important treatment for fatty liver, such as vitamins B, C, E, lecithin, etc. The selection of lipid-lowering drugs should be cautious, as they may aggravate liver damage. Therefore, it is generally believed that: mild fatty liver can be treated without medication for a while, and the main focus is to adjust the diet structure and strengthen exercise.