No matter where gout occurs, anti-inflammatory and pain-relieving drugs and uric acid-lowering drugs are conventional treatment drugs, but they need to be used selectively under the guidance of a doctor according to the degree of the disease. For gout patients with acute attack, rapid relief of joint swelling and pain is the main treatment principle, and generally non-steroidal anti-inflammatory painkillers, colchicine, glucocorticoids and other drugs can be used. Among them, non-steroidal anti-inflammatory painkillers should be the first choice, but need to pay attention to the cardiovascular and gastrointestinal adverse reactions of drugs. If there are contraindications to NSAIDs, colchicine can be chosen, but it should be noted that colchicine has a high incidence of gastrointestinal adverse reactions. If the patient’s condition is severe, conventional drug therapy is not effective, or there are contraindications to the use of NSAIDs and colchicine, short-term use of glucocorticoids may be considered. For patients in intermittent and remission periods, the use of uric acid production inhibitors or uric acid excretory agents, such as febuxostat, allopurinol, and benzbromarone, is mainly required. In addition, traditional Chinese medicine and proprietary Chinese medicine are also effective in the treatment of gout, which can relieve joint swelling and pain and lower blood uric acid. Therefore, no matter where gout occurs, anti-inflammatory and pain-relieving drugs and uric acid-lowering drugs are still the first choice for treatment, but whatever drugs are applied should be used under the guidance of rheumatologists.