High blood lipids will not cause nephritis, but long-term high blood lipids will indirectly cause kidney lesions. Long-term high blood lipids will lead to atherosclerosis, and atherosclerosis of renal arteries will cause renal hypertension or kidney atrophy, and renal hypertension in turn will aggravate kidney lesions. In addition, atherosclerosis caused by high blood lipids will lead to a decrease in blood vessel elasticity, which will eventually lead to an increase in blood pressure and cause hypertension. If hypertensive disease cannot be effectively treated and let hypertension exist for a long time and continuously, it will make the glomerular internal capsule pressure rise, glomerular fibrosis and atrophy, glomerulosclerosis leading to renal parenchymal ischemia and renal unit reduction, resulting in hypertensive nephropathy, and chronic renal failure is one of the serious consequences of long-term hypertensive disease with poor prognosis.