Paraquat (English: Paraquat), also known as paraquat, gramoxone and baragari, is an herbicide. The chemical name is “1,1′-dimethyl-4,4′-bipyridinium chloride”, chemical formula C12H14Cl2N2, which is made by the reaction of pyridine, sodium metal and dimethyl sulfate. Easily soluble in water. It has tactile and conductive effects, and fails quickly after contact with soil, so it is a kind of herbicide that has no harm to soil. At present, it is used in many places in rural areas of China. However, users do not know its lethality, especially for those who take it orally, no matter men, women or children, they may die if they take a small sip (about 15ml) of the original solution, which is the finished product sold in the market, so some developed countries have abolished the use of paraquat. Since there is no special medicine for paraquat poisoning, it can only be prevented and its extremely high lethality rate should be strongly publicized. After poisoning occurs, we can do the following treatment: 1. Skin surface contamination should be removed from contaminated clothing and washed thoroughly with soap and water before washing with water. Eye contamination with 2% to 4% sodium bicarbonate solution rinse 15min and then wash with saline. 2, accidentally taken by mouth at the scene should immediately take soapy water, both to induce vomiting and to promote paraquat inactivation. White clay (30%) or soap clay can absorb paraquat, but it must be taken within lh to be more effective. If there is no white clay (also called bleaching clay) or soap clay, common clay can be used to take mud water after filtering with gauze, or adsorb with activated carbon (every 100g white clay or soap clay can adsorb paraquat about 6g). Gastric lavage should be gentle, and the lavage solution should be chosen from 2% to 5% sodium bicarbonate solution with appropriate amount of soap solution or washing powder to promote the deactivation of toxic substances, and it is better to use manual aspiration type, and the amount of liquid exchanged is 200-300ml each time, and it is not advisable to use automatic gastric lavage machine with no pressure indication alarm in instillation type, which is because paraquat has greater corrosive effect. After gastric lavage, 30g of activated carbon suspension can be given again and salt laxative can be used to induce diarrhea. 3. Blood poisoning is better cleared by hemoperfusion than hemodialysis, because the peak concentration of poison in blood after dog poisoning is 70-120min, so the earlier it is used, the better. Japanese scholars advocate active hemoperfusion, i.e., receiving no less than 10h of hemoperfusion treatment within 24h after poisoning, and believe that starting within 15h of poisoning and making hemoperfusion treatment for 10h continuously can effectively improve the survival rate of patients.