When it comes to “vulvar leukoplakia”, I believe we can all associate it with hypopigmentation of the vulva, but the most troubling aspect of “vulvar leukoplakia” is the long-term stubborn itching of the vulva. Although “vulvar blemish” is not uncommon, many patients are often ashamed to talk about it due to its intimate location and are reluctant to seek treatment in time. On the other hand, the lack of professional vulva clinics in China has led to the majority of patients having nowhere to turn to for medical help or to turn to the doctor in a hurry, and the so-called “miracle drugs” and “prescriptions” have been tried once without any improvement. This circle makes many patients do not get timely diagnosis and effective treatment, physically and psychologically suffer from vulvar itching, serious lesions and even unable to have sex and affect the relationship between the family couple, individual patients also have the risk of cancer. Therefore, it is said that “vulvar leukoplakia is not cancer, but it is more painful than cancer.” Although it is a so-called “minor disease”, its potential harm can not be underestimated.