Early symptoms of motor neuron disease are not obvious, patients can walk a longer distance, more or less the same as normal people, but the development of the disease and the different parts of the injury, patients can have symptoms such as muscle weakness, muscle atrophy, which affects the walking distance, or even can not walk. In the case of motor neuron injury, the course of the disease develops gradually. In the early stage of the disease, due to the lightness of the injury, it is not easy to be detected, and the patient can walk normally with no obvious difference from normal people; when the injury is more serious, it means that the disease has already developed to the late stage, and the patient may develop symptoms such as muscle weakness and muscle atrophy, which will develop into paralysis to the extent that the patient can’t walk. The course of the disease is generally slow, and the patient’s progression from normal walking to not being able to walk is gradual. When motor neuron injury occurs, it is necessary to go to the hospital in time for early detection and treatment to slow down the progression of the disease, and take appropriate methods of intervention under the guidance of the doctor.