Motor neuron disease is categorized as impotence in Chinese medicine. The treatment of motor neuron disease is usually based on the use of Chinese herbal formulas such as Clearing Dryness and Rescuing Lungs Soup, Jiawei Ermiao Pill, and tonifying the middle and benefiting the vital energy. 1. Clearing Dryness and Rescuing Lungs Soup: It is suitable for the impotence syndrome of Lung Heat and Fluid Injury (heat in the lungs that continuously depletes the body’s fluids), which consists of Mulberry Leaves, Gypsum, Humulus, Loquat Leaves, Colla Corii Asini, Ginseng, Maitake, Apricot Kernel, and Glycyrrhiza glabra, and it can clear dryness and moisten the lungs, and benefit the qi and nourish yin (tonifying the qi and nourishing yin fluids). It should be noted that spicy and stimulating food should be avoided during the period of use. 2. Jiawei Ermiao Pill: Suitable for impotence evidence of dampness-heat immersion, the formula consists of Cangzhu, cypress, hyssop, Fangji, Angelica sinensis, castor seed, tortoise board, and ripened rhizome, which can clear away heat and dry up dampness (removing heat and drying up dampness). When using it, it should be noted that smoking, alcohol, spicy and greasy food should be avoided while taking it. 3. Tonifying the middle and benefiting qi soup: suitable for impotence among the spleen and stomach weakness, the formula consists of astragalus, atractylodes macrocephala, chenpi, aspergillus, chaihu, ginseng, angelica, licorice, can tonify the middle and benefiting qi, ascending yang lifting the sinking (ascending to lift up yang qi, in order to lift up the sinking organs). When used, it should be noted that it should not be taken by patients with colds and fever. Patients with impotence symptoms are advised to visit regular hospitals for treatment under the guidance of professional doctors for evidence-based treatment if necessary.