Precocious puberty refers to the appearance of secondary sexual characteristics in boys before the age of 9 and in girls before the age of 8. Precocious puberty is a common clinical developmental problem with both physiological and psychological effects, and precocious puberty in children caused by environmental estrogens has also attracted attention, and the milk powder incident has made precocious puberty a focus of attention. exceed the actual age, linear growth is maintained at the corresponding age level, insist on follow-up every 3 months, if the bone age growth exceeds the age growth, review the bone age every 6 months if necessary to detect abnormalities in time and to intervene as necessary. Sexual development occurs after the age of 8 for girls and 9 for boys at normal age. If sexual development progresses rapidly, the time to progress from one developmental stage to the next is shorter, the growth rate increases, and the bone age significantly exceeds the actual age within a short period of time, which affects the final adult height due to early healing of the epiphysis. For rapidly progressive pubertal development, i.e., the appearance of rapid bone age progression and significant impairment of predicted adult height should be intervened in a timely manner according to the precocious puberty protocol. The appearance of secondary sexual characteristics in infants and young children, also called “micro puberty”, is mainly characterized by breast development, early appearance of pubic hair, vaginal bleeding, etc. Children with early appearance of pubic hair who also have other signs of androgen excess, such as enlarged clitoris and accelerated growth, should pay attention to exclude congenital adrenal cortical hyperplasia and masculine tumors, while infants and young children with breast In infants and young children, breast development is usually associated with premature mammary gland development, McCune-Albright syndrome, and exogenous precocious puberty. Premature mammary gland development is unilateral or bilateral breast enlargement, or alternate enlargement of both mammary glands, receding, without other signs of sexual development, without growth acceleration, uterine enlargement, changes in vaginal mucosa, etc., mostly seen in girls before 2 years of age, with enlarged mammary glands but no nipples, deepened areola pigmentation, very slow growth of breast tissue, which can last for several months before receding, some of which can last until puberty, appearing several months after the receding of breast tissue The level of serum luteinizing hormone and estrogen are at the prepubertal level, the level of follicle stimulating hormone and inhibitory hormone can be increased, the level of FSH can be significantly increased, but the level of LH is not significantly increased, the precocious breast development is incomplete precocious puberty, 13.5% – 18.4% of the children will develop into central precocious puberty, the precocious breast development, especially the enlargement of the breast does not recede. If there are other sex symbols, accelerated growth, advanced bone age, and elevated sex hormone levels, the child should be evaluated and treated promptly. In exogenous precocious puberty caused by ingestion of exogenous estrogens, girls or boys develop breasts with nipple areola and pigmentation of external genitalia, girls present increased vaginal discharge and even vagina appears asymmetrical to breast development, and some children may have a clear history of misuse of estrogen-containing drugs, food or exposure to estrogen-containing cosmetics. Some scholars believe that some phytoestrogens and other environmental endocrine disruptors such as pesticides and collaterals can play estrogen-like roles in the body and have the potential to cause mammary gland development or abnormal sexual development in infants and children. Most of them are idiopathic central precocious puberty. Girls with central precocious puberty who start to promote the development of secondary sexual characteristics at the age of 6–8 usually have no organic lesions of the central nervous system, and the proportion of central nervous system abnormalities in girls with central precocious puberty who develop sex before the age of 6 is 20%, and the younger the age, the greater the possibility of imaging abnormalities. The purpose of treatment for precocious puberty is to inhibit the process of sexual development, delay skeletal maturation and improve the final adult height, avoid early menarche and related psychosocial and behavioral problems caused by precocious puberty, and to treat male children younger than 9 years old and female children younger than 8 years old. Children with linear growth, skeletal maturation and secondary sexual characteristics are accelerated, and children with rapid development of secondary sexual characteristics whose predicted adult height is shorter than normal by 2 standard deviations should be treated, while children with slow sexual development, bone age growth in line with age growth, or children with normal growth rate despite early bone age should be closely followed up and observed, and once the treatment criteria are reached, timely intervention should be made to reduce the loss of adult height. The loss of adult height can be reduced. How to avoid precocious puberty is an issue of great concern to every parent, and it is recommended that children: 1. avoid excessive animal foods. Excessive intake of animal-based foods not only predisposes children to obesity, but often also to excessive intake of additives in animal feed. This is probably the most common reason for the current increase in precocious puberty year by year. At the same time, with the aggravation of environmental pollution, pollutants may also enter the body of animals, obese children, precocious puberty is more obvious than normal children. 2, do not eat anti-seasonal vegetables and fruits. Winter strawberries, grapes, watermelon, tomatoes, etc., early listing of pears, apples, oranges and peaches in late spring, almost all in the “ripening agents” to help anti-seasonal or early ripening, must be avoided for young children to eat. Too brightly colored fruits, often induced by ripening agents, should also be avoided. 3, do not eat tonic food including cordyceps, ginseng, ginseng, etc.. Chinese medicine points out that the more tonic class of medicine, the easier it is to change the normal endocrine environment of the child, resulting in an imbalance in their physical and mental development. Other things such as: pupae, chicken embryos, placenta, royal jelly, colostrum, pollen preparations nutritional tonic is a common cause of precocious puberty. 4, fried food. Especially fried chicken, French fries and potato chips, excessive heat will be transformed into excess fat in children’s bodies, triggering endocrine disruption, leading to precocious puberty; and, after repeated heating of edible oil, high temperatures make its oxidative denaturation, is also one of the causes of “precocious puberty”. Children who often eat fried puffed food, “precocious puberty” is 2.5 times the likelihood of ordinary children. 5, some drinks, for children marketed as “taller and stronger or increase appetite” drinks or beverages, so that children at the age of five or six grow taller and stronger than children of the same age, their bone age may have reached 8 or 10 years old. And when the child enters the normal development stage, but do not see the growth. There are also some health products (national regulations, health products are not allowed to promote any therapeutic effect), such as what protein powder, unless suffering from some special diseases, normal children simply do not need to use, now children, protein intake is often too much. 6, of course, in addition to food, supplements, health products, there are some possible causes of precocious puberty. For example, excessive light is one of the important causes of precocious puberty in children, especially prolonged light at night will affect the normal work of the pineal gland, an endocrine organ in the brain, which may lead to early secretion of gonadotropins, resulting in precocious puberty. The extensive use of cosmetics, the proliferation of bad information (including text information, media information, network information, cell phone information, language information, etc.), environmental pollution, and the excessive use of chlorine-containing pesticides are also important causes of increased precocious puberty. Individuals are also caused by misuse of contraceptive pills. Therefore, if you have similar drugs or health products at home, make sure to collect them to avoid your child from taking them by mistake. If your child has precocious puberty, do not be too anxious, suspect this and that, or blame the child, as long as you go to a professional growth and development specialist clinic in a timely manner, and listen to the correct guidance of the doctor, to reduce the dual harm to the child, and promote the healthy growth of the child.