Recently, there are children with precocious puberty coming to the clinic, through communication with parents found that many of their parents due to overindulgence in children, afraid of children’s development than their peers, and premature use of supplements, further aggravating the formation of precocious puberty. Children with precocious puberty should be cautious with supplements. There are many Chinese medicine supplements that can promote precocious puberty, which should be used with caution, as listed below: 1, animal drugs: antler, antler, antler gum, antler cream, purple river car, sea dog kidney, seahorse, sea dragon, mealybug, gum, beehive. 2.Plant drugs: red ginseng, Radix et Rhizoma Tenuifolia, Radix et Rhizoma Puerariae, Radix et Rhizoma Cimicifugae, Herba Epimedium, Cordyceps Sinensis, Ephedra, Rhizoma Bacopa, Herba Cistanches, Rhizoma Locusta, Fenugreek. 3, food drugs: soybean, dried cinnamon, dried lychee, royal jelly, silkworm chrysalis, beef, dog meat, mutton, sparrow, pigeon, quail, crow’s nest, fish glue, pollen, snapper. 4, ore-type drugs: Yangqi stone, amethyst, andrographis.