Striking pediatric poisons

According to statistics, the domestic drug market exists hundreds of Chinese medicines containing cinnabar and staminaria ingredients, scientifically confirmed that cinnabar and staminaria are toxic to humans, while their legendary curative effects have not been scientifically proven, rather than calling them “medicinal materials”, rather than “poisons”. The most alarming thing is that The most alarming thing is that these “poisons” containing vermilion and stellaria are not only taken in large quantities by adults, but are even widely used as pediatric drugs for children who have no choice. The following is some research information on cinnabar, stannum and related Chinese medicines: [Cinnabar] is also known as cinnabar and tansa, a natural ore of mercury sulfide. Cinnabar is a very important traditional Chinese medicine in Chinese medicine, used for the so-called “tranquilization and sedation”. Shennong Ben Cao Jing: sweet in taste, slightly cold, non-toxic. It is used to nourish the spirit, calm the soul, benefit the qi, brighten the eyes, and kill evil spirits. Compendium of Materia Medica: Nourishes the heart, heart and blood, kidneys, spleen, and fetus, detoxifies, and can be used for sweating. If you open any Chinese medicine book, there are a lot of absurd prescriptions containing vermilion. Until today, “Chinese Pharmacopoeia” and “Ministry of Health Ministerial Standards”, containing vermilion prescription preparations up to hundreds of species, pediatric drugs also have more than a hundred, the proportion can account for about 10%, pediatric drugs are a little higher. Cinnabar is also common in Mongolian and Tibetan medicines. Modern biomedicine found that cinnabar is absorbed through the digestive tract or wounds, generating free mercury, and combined with hemoglobin in the blood, with the blood circulation into the body’s various tissues and organs. Free mercury binds to tissue cells (including the central nervous system and enzyme system), causing malnutrition, degeneration, and even necrosis of the cells. Acute poisoning is manifested by nausea, vomiting, abdominal pain, diarrhea, pus and blood, oliguria, urinary shutdown, and uremia. Chronic poisoning manifests as digestive system lesions, psychiatric abnormalities, mercury toxic tremors, liver and kidney impairment, reduced visual field, and decreased sexual function. Clinical reports indicate that liver and kidney damage, gastrointestinal reactions, neurotoxicity, hemolytic anemia, and allergic reactions may occur with the use of vermilion. Some animal tests have reported that vermilion can reduce the excitability of the central nervous system in mice, so it has a so-called “sedative and sleeping” effect; however, vermilion has a cumulative effect in the body, and when administered for a long time, animals show symptoms such as weight loss, hypermobility, unresponsiveness, renal ischemia, and liver enlargement. Chinese medicine is to take some of the toxic side effects of vermilion as a curative effect, which is the reason why vermilion in pediatric medicine abuse in “tranquilizing and calming”. The current TCM community does not deny the fact that vermilion is toxic, but it is very divisive. When TCM doctors need to boast about the efficacy of the vaporous vermilion, they say, “Maybe those soluble ingredients are effective”; if you want to talk to a TCM doctor about the toxicity of vermilion, he will talk to you about “vermilion water flying process, remove all soluble mercury salts The remaining HgS is insoluble, not absorbed, and 98% is excreted directly from the body”. According to the Chinese Pharmacopoeia 2000 edition, the purity of HgS in vermilion shall not be less than 96%, other impurities are soluble mercury salts, arsenic, lead, cadmium and other heavy metal companion compounds, which is the reason that when the Chinese patent medicine with vermilion ingredients is caught abroad, it is often found that the lead exceeds the standard at the same time. In addition to this small amount of soluble mercury salts, according to the results of Shou Guang Shun and other studies: “Cinnabar internal overdose toxic is certain, the human inorganic mercury absorption rate of 5%, methyl mercury absorption rate can reach 100%, cinnabar (HgS) in anaerobic conditions with sulfur, pH7, temperature 37 ℃ in the dark environment with methyl substances can produce methyl mercury. The human intestinal tract is equipped with this condition, so the internal consumption of cinnabar and preparations increase the chance of poisoning”. The Chinese Pharmacopoeia 2010 edition also had to clearly indicate: “Pregnant women and those with liver and kidney insufficiency are prohibited”; the problem is that you are willing to take a fully functional liver and kidney to try this tiger and wolf medicine that you know has liver and kidney toxicity? # vermilion poisoning case 1 # baby girl, born healthy, day 6 mother found horse teeth, grandmother picked off with a needle prick, and then put on vermilion (about 4-5 grams), after the child began to restlessness, crying and mouth salivation, about 1 hour later the child fell asleep, about 2 hours found pale, shallow slow breathing, sometimes deep inhalation, gradually see the face gray, the mouth around the green, and appeared once a convulsion, a general spasmodic, double eye gaze …… eventually died. (Journal of Neonatology, 1993, No. 05, “A case of acute vermilion poisoning in a newborn”) #Vermilion poisoning case 2# Female, 3 months, parents gave about 500mg of vermilion because she was crying and fussing, then gradually appeared drowsy, limbs weak, sometimes moaning. After about 20 hours, she became comatose and did not respond to various stimuli, and came to the clinic urgently. During this period, he was confused and in a deep coma. His breathing was shallow and slow with irregular rhythm, apnea, pallor, double eye gaze, equal pupils, and decompensated metabolic acidosis. (Pediatric Emergency Medicine, No. 03, 1997, “Vermilion Acute Poisoning 1 Case”) #Vermilion Poisoning Case 3 Skin Absorption #6-month-old male infant was diagnosed with indigestion by a Chinese medicine practitioner, and various drugs were used for navel paste and sizzling, and the infant died on the day of navel paste with vermilion. On examination, large areas of renal proximal and distal tubules were degenerated and necrotic, and hepatocytes were degenerated and swollen. The mercury content was determined to be 452μg/100g kidney tissue and 29μg/100g liver tissue. (Journal of Forensic Medicine, November 1998 (No. 4) “One case of vermilion poisoning causing death” by Yang Zhenglong) – The mercury and its compounds in vermilion can enter the body through the skin and can cause harm to children regardless of the dose, just to varying degrees. Xiong Huang] Xiong Huang is an arsenic sulfide mineral, and the Compendium of Materia Medica believes that “(Xiong Huang) treats malaria and cold fever, dysentery in the summer, fetid drinking, epilepsy, dizziness of the head wind, resolves blood stasis in the abdomen, and kills labor worms and noma worms.” Modern medicine has confirmed that arsenic and its compounds can cause arsenic poisoning, damage to nerves and blood vessels, and can cause fatty degeneration and necrosis and carcinogenesis of parenchymal organs such as the liver, kidneys, spleen and heart muscle. Some TCM enthusiasts are fond of arsenic for acute promyelocytic leukemia, and it must be pointed out that the mechanism and clinical application of arsenic for acute promyelocytic leukemia is dependent on modern medical confirmation; the genus is a drug whose benefits outweigh the risks before a better and safer potent drug is discovered; clinical treatment is just as likely to have severe arsenic poisoning, only it is worth trying compared to losing one’s life. Normal countries internationally have banned the use of heavy metals such as cinnabar and staghorn in medicines, and there are strict trace limits for mercury and arsenic in medicines and food …… The National Essential Medicines Catalogue (2012 edition) (Ministry of Health Order No. 93), which was last issued by former Health Minister Chen Zhu before he left office, also includes medicines containing cinnabar and staghorn Chinese patent medicines, which can be paid by medical insurance, include at least the following: Niuhuang Detoxification Pill (capsule, soft capsule, tablet), Tianwang Tonic Heart Pill (tablet), Paozi Yangxin Pill, Hua Tuo Zai Zai Wan, Xiao Wu Luo Wan, Bing Boran, Qi Li San (capsule), An Brain Pill, Suhe Xiang Pill, Chasing Wind and Bone Pill, Wounded Bone Pill …… The Ministry of Health issued Chinese Patent Medicine The standard of prescriptions of pediatric medicine containing cinnabar or stellate yellow is included in the Standard of Formulas Ding convulsions and wind pills, Pu Ji Hui Chun Wan, Pediatric Baishou Wan, Pediatric Bao Bao Bao Wan, Pediatric Hui Chun Wan, Pediatric acute frightening san, Pediatric Jin Dan Tablet, Pediatric Niuhuang San, Pediatric Zhen Zhen Zhen Wan, Pediatric Amber Wan, Zhi Sheng Bao Yuan Wan, An Brain Niuhuang Tablet, Bai Xiu Wan, Hui Chun Dan, Snake Injury Relief Tablet, Doll Ning, Pediatric Liang You San, Pediatric Antelope San, Pediatric Niuhuang Qing Xin San, Pediatric Taiji Pills, Paediatric Anti-accumulation Pills, Infant Ping (Capsules) [Drama], Nursing Baby Pills, Zhupeo Panic Wind Pills, Eight Treasures Yu Shu Pills (Eight Treasures Yu Shu Dan), Tangled Throat Pills, Paediatric Drawings Pills, Paediatric Pneumonia Pills, Paediatric Four Diseases Pills, Infant An Tablets, Zhupeo Bao Bao Infant Pills (Zhupeo Bao Infant Dan), Bao Yuan Pills (Bao Yuan Dan), Ginseng San Qi Injury Pills, Panic Wind Pills, Green Snow, Niuhuang Qing Fever Pills, Taihe Miao Ling Pills (Taihe Miao Ling Dan), Peach Blossom Pills, Hygiene Bao Pills (Hygiene Bao Dan), Pediatric Qi Ying Pills, Pediatric Heat Clearing and Calming Pills, Fever Purging Tablets, Pediatric Navel Wind Pills, Pediatric Calming Pills, Infant Protection Pills, Emergency Relief Pills, Tie Wa Pills (Tie Wa Dan), Pediatric Bai Le Tablets, Pediatric Heat Clearing Tablets, Infant Ning Pills, Compound Snake Gall Bladder and Chen Pi Powder, Pediatric Jin Dan, Infant Dissipative Pills, Bao Tong Phlegm Pills, Infant Protection and Calming Pills, Gao Li Qing Xin Pills, Ginseng Zhi Bao Pills, Wan’s Niuhuang Qing Xin Tablets, Pediatric Lung Heat Ping Capsules, Paediatric Gourd San, Salt Snake San, Paediatric Pao Lung Ning (San), Paediatric Pao Lung Ning Capsules, Paediatric Ping (San), Musk Pill, Paediatric Chilisan, Throat Medicine San, Hu’s Six Gods Pill, Niuhuang Qinghe Capsules, Qianjin San, Snake Gall Bladder Chen Pi Phlegm Resolving San, Amber Phlegm Resolving Calm Pill, Ginseng San Qi Injury Medicine (San), Paediatric Panic An Pill, Jiulong Hua Feng Pill, Bureau Fang Zhi Bao Pill, Paediatric Hui Chun Pill (Large Honey Pill), Paediatric Panic Chilisan, Pediatric Zhu Huang San, Zhu Pu An Shen Dan (pills), Jin Yi Bao Ing, Panic Wind San, Pediatric Niu Huang Granules, Coughing Tao Hua San, An Brain Pills, Niu Huang Jing Brain Tablets, Pediatric Anti-Shock Tablets, Zhen Zhen Pan, Gua Qi San, Angong Niu Huang Tablets, Eight Treasures Five Gall Bladder Medicine Mo, Niu Huang Xi Antelope Pills, Bao Chi One Grain Gold Pills, Ginseng San Qi Injury Medicine San, Plus Flavor Snake Bile Chen Pi Tablets, Niu Huang Ning Gong Tablets, Pediatric Hundred Effect Tablets, Pediatric Phlegm Pills, Pediatric Panic Wind Tablets, Awakening Brain An Shen Capsules, Wounded Bones Tablets, An Brain Tablets, Dotted Tongue Pills (Plum Blossom Dotted Tongue Dan), San Qi Blood Injury Ning Ning Capsules, San Qi Blood Injury Ning San, Fast-acting Niuhuang Pills, Niuhuang Awakening Brain Pills, Yun Xiang Jing, Green Snow Capsules, Taiji Pills, Pediatric Seven Precious Pills (Pediatric Seven Precious Dan), Yu Shu San, Antelope Qing Lung Pills, Niuhuang Qing Lung Tablets, Clear Heat and Set Alarm Pills, Sheng Hua Red and Black Pills, Pediatric Fever Relief Pills, Pediatric Seven Precious Tablets …… The Chinese Pharmacopoeia 2005 Edition includes pediatric prescriptions containing cinnabar or stellaria An Gong Niu Huang San, An Gong Niu Huang Wan, Bao Chi San, Bureau Fang Zhi Bao San, Niu Huang Ba Long Wan, Niu Huang Qian Jin San, Niu Huang Zhen Zhen Wan, Wan’s Niu Huang Qing Xin Wan, Gastrointestinal An Wan, Xiang Su Zheng Gastric Wan, Pediatric Jin Dan Tablet, Pediatric Panic San, Pediatric Clear Fever Tablet , Pediatric Zhi Bao Pills, Medical Epilepsy Pills, Zi Xue, Amber Holding Dragon Pills, Gua Sha Medicine. Containing Xiong Huang ingredients of pediatric Niuhuang San Ministry standards and the Chinese Pharmacopoeia included adult prescriptions containing cinnabar or Xiong Huang Er Yi Pills, Live Loose Pills, Epilepsy and Tranquilizer Pills, Toadstool Ingredient, Banyun San Eye Medicine, Chang Yi Pills, Pulse Loop Tong, Niuhuang An Xin Wan, Niuhuang Eight Treasure Pills, Qing Xin Rolling Phlegm Pills, Qing Xin Wan, Rhinoceros Horn and Poison Pills (Rhinoceros Horn and Poison Dan), Heart and Brain Tranquilizer Tablets, Waking Brain and Lowering Blood Pressure Pills, Nourishing Yin and Tranquilizer Tablets, One Grain of Pearl, Nourishing Ginseng and Antler Pills, Eight Treasures Zhen Zhen Pills, Bari San, Changchun Red Pill Tablets, Fei Long Zuifeng Pills (Fei Long Zuifeng Pills), Guang Xie San (Rhinoceros Antelope Pills), Anti-embolism Reconstructive Pills, Long Brain Tranquilizer Pills, Turbine Returning Spring Pills, Sanitation Pills, Wu Hong Ling San (Wu Hong Ling Dan), Sucking Urine Pills, Tranquilizer Warming Gall Pills, Bao Chi One Grain of Gold Pills, Nourishing Kidney and Brain Capsules, Tonic Heart Tablets, Gaiyi Capsules, Hui Sheng First Pills (Hui Sheng First Dan), Hui Tian Zai Zai Pills, Niu Huang Qing Brain Pills, Niu Huang Yuzhen Pill, Fruits and Blood Tonic Heart Pill, Pearls and Myocardium Pill, Zhen Ling Pill, Zhen Epilepsy Tablets, Eight Treasures Pill, Goose Feather Tube Eye Medicine, Gua Zi Ingot, Relief Table Chasing Wind Pill, Antelope Pearl Pill, Ren Dan, Zhu Huang Eight Treasures Pill, Musk Bone Capsules, Eight Treasures Plucked Cloud Pill, Eight Treasures Eye Medicine, Ting Xin Pill, Secret Shu Liver Pill, Niu Huang Qing Gong Pill, Bone Calming Pill (Bone Calming Pill), Wan Ling Tablets, Zhuan Yuan Pill, Exorcising Wind and Phlegm Pill, Gua Sha Medicine Toad Pill, Bai Yi Zhen Zhen Panic Pill, Pai Zi Yang Xin Tablets, Bao Bao Wan Ling Dan (Pill), Detoxification Wan Ling Wan, Jiuzhi Qing Xin Wan, Female Sheng Jin Dan, Ping Liver Shu Luo Wan (Ping Liver Shu Luo Dan), Injury Tincture, Zhen Huang An Gong Tablets, Pearl Bing Boran, Zhu Sha An Shen Tablets, Zi Jin San, Epileptic Dragon and Tiger Pill, Hui Sheng Zai Zai Wan, Li Xin Wan, Shu Liver Pill (Concentrated Pill), Tian Wang Tonic Heart Pill, Painful Swelling Spirit (Tincture), Bao Long Wan, Ha Meug Ting Qi Wan, Hui Sheng First Dan Capsules, Pearl Niuhuang San, Nourishing Kidney and Beneficial Brain Tablets, Magnetic Zhu Pills, Sore Throat Pills, Monkey Date Niuhuang San, Rescue Panic Pills, Niuhuang Anti-inflammatory Spirit Capsules, Niuhuang Anti-inflammatory Spirit Pills, Qingjin Lixin Pills, Qingdian Pills, Sanhuang Bao Wax Pills, Zhenxin Anshin Pills, Vermilion Anshin Pills, Ginseng and Ginseng Gouben and Shao Pills, Jiawei Qilisan, Summer Vaccination Tablets, Expelling Wind and Suhe Pills, Suhe Pills, Phlegm and Asthma Half Xia Granules (Punch), Tong Ren Anshin Pills (Vermilion Anshin Pills), Topical Zijin Ingot, Wind-tracing and Bone Penetrating Tablets, Brain-supporting and Tranquilizing Tablets, Compound Deer Fetus Pills, Golden Yellow Holding Dragon Pills, Green Calyx Pointing Tongue Pills, Qing Yu Fei Fei Dan, Ten Fragrant Ting Pain Pills, Diarrhea and Belly Pain Capsules, Musk San Miao Paste, Gao Li Qing Xin Pills, Niuhuang Holding Dragon Tablets, Qi Pain Pills, Stroke and Reclamation Pills, Musk Niuxiang Pills, Drop and Strike Pill Wine, Diarrhea and Belly Pain Pills, An Shen Tonic Qi Pills (Concentrated Pills), Compound Toadstool Pills, Kang’s Niuhuang Detoxification Tablets, Ling Bao Ru Yi Pills, Ginseng Reclamation Pills (Concentrated Pills) Musk Xiong Zhi Bao Pills, Foshan Ginseng Reconstruction Tablets, Jin Niu Eye Medicine (Disperse), Jiu Qiang Brain Li Qing (Beijing Brain Li Qing), Liang Caixin Drop Pills, Miao Ling Pills, Ginseng Reconstruction Pills (Honey Pills), Niu Huang Qing Xin Pills, Bo Zi Yang Xin Pills, Bao Long Pills, Fever Avoidance Pills, Bing Bor Pills, Kidney Beneficial Brain Tablets, Pure Yang Zheng Qi Pills, Twenty-five Flavor Coral Pills, Twenty-five Flavor Song Shi Pills, Red Spirit Pills, Plum Blossom Dotted Tongue Pills, Niu Huang Qing Xin Pills (Bureau), Heping Liver Shu Luo Pill, Qi Li San, Ginseng Reclaiming Pill, Ten Fragrant Returning Pill, Shu Liver Pill, Heat Stroke Tablets, Su He Xiang Pill, Tian Wang Tonic Heart Pill, One Pill for Toothache, One Twist of Gold, Yi Yuan San, Zi Jin Zhen. The Ministry of Health Ministry standard Tibetan medicine volume and pharmacopoeia included in the prescription containing cinnabar or stellaria Twenty-five flavors of Marble Pills, Twenty-five flavors of Coral Pills, Twenty-five flavors of Ghostly Pills, Twenty-six flavors of Tongjing Pills, Twelve flavors of Ice Pills, Seventeen flavors of Dapeng Pills, Thirteen flavors of Safflower Pills, Fourteen flavors of Antelope Horn Pills, Seven flavors of Rabbit’s Ear Pills, Eight flavors of Qinpi Pills, Eight flavors of Western Safflower to stop bleeding, Lung Heat Pu Qing Pills, Sa Heat Dapeng Pills, Eighteen flavors of Ou Qu Zhen Bao Pills, Sitzhu Daxi (Note that the mercury content of some Tibetan medicines is added through a complex semi-processed substance called “Zotai/Sattai/Zota/Zotai”.) The Ministry of Health’s Ministry of Health Standard Montessori medicine volume and pharmacopoeia included in the prescription containing cinnabar or andrographis Jixiang Ankun pill (Uliji C18), ulcer ointment (Hata each its C7), external ulcer powder (Hata each its C7), western saffron sixteen flavor powder (Gu Ri Gumu C16) Nowadays, there is a popular saying in society: “Do not let your children lose at the starting line. ” There is no worse behavior than to let your young child take poison. So, love your child, please don’t give him/her poison in the name of love, don’t let your child lose at the starting line!