Ankylosing spondylitis is a systemic disease characterized by chronic inflammatory lesions of the mid-axis joints (sacroiliac joints and spinal attachment points) and is a seronegative spondyloarthropathy. The history of the disease varies from six months to 20 years, and the ratio of men to women is about 4:1 ankylosing spondylitis belongs to the category of rheumatic diseases. The cause of this disease is still unclear, with the spine as the main lesion of the chronic disease, involving the sacroiliac joint, causing spinal ankylosis and fibrosis, resulting in varying degrees of eye, lung, muscle and bone lesions, is an autoimmune disease. Ankylosing spondylitis is a relatively common disease with a protracted course, so early diagnosis and treatment should be pursued. Young people aged 16-25, especially young men, should be particularly alert to the possibility of ankylosing spondylitis if they develop the following symptoms The pain in the lumbar and sacral areas is usually accompanied by a stiffness in the lower back, which is apparent in the morning and can be relieved by activity. There are also cases of knee, ankle, heel, and sciatica pain. Therefore, it can be easily confused with synovitis of the knee and lumbar leg pain. In young men aged 12 to 30 years, persistent or intermittent pain in the lumbosacral and hip joints, accompanied by a feeling of lumbar stiffness and limited bending and squatting, or unexplained pain in the small joints of the heel, thoracic cord, cribriform spine, temporomandibular, stalk, and metatarsal phalanges should be considered as ankylosing spondylitis. 20% to 30% of patients have acute anterior uveitis or iritis, and 75% of patients have acute anterior uveitis. The diagnosis of this disease is not difficult, as most patients can be diagnosed with a clear orthopantomogram of the pelvis. Grade 1: showing erosion and sclerosis of bilateral sacroiliac joints; Grade 2: showing obvious erosion and sclerosis of sacroiliac joints with worm-like changes and small cystic translucent shadow under the joint surface, but the joint space changes are not significant; Grade 3: showing widening of the joint surface, sclerosis of bone around the gross, and partial bony ankylosis; Grade 4: showing disappearance of sacroiliac joint space with bone lines through the periarticular sclerosis. ct has CT performance is usually graded from 0 to 4 with reference to the X-ray grading scale.1 Grade 0: normal; Grade 1 (suspicious changes): blurred iliac joint surface, focal osteoporosis and mild subchondral bone erosion and erosion, but normal joint space; Grade 2 (mild abnormalities): blurred joint surface, small limited erosion, small cystic changes and limited bone thinning Grade 3 (marked abnormality): moderate or progressive sacroiliac arthritis with marked subchondral bone erosion, destruction and hyperplasia, marked bone thinning and cystic changes, jagged and beaded joint margins, widened or narrowed joint gaps, and partial joint ankylosis; Grade 4 (severe abnormality): all joints show severe bone destruction, hyperplastic sclerosis and marked bone thinning, and complete joint ankylosis. Early diagnosis and early treatment are very important to improve the cure rate and reduce the disability rate. For atypical cases, it is important to go to the hospital for examination in order to clarify the diagnosis as soon as possible, so as not to bring about unpredictable and serious consequences and endanger the health of the body. We all know that Jay is an ankylosing spondylitis patient, and he does not tell his fans “I am a patient, I am in pain” every time he sings. It is because of the illness that you have to be strong. Always remember this phrase.